Detection of EBV DNA in peripheral blood of LTx recipients with and without PTLD by Q-PCR
| Patients . | Total samples tested, no. . | Samples above cut-off value in Q-PCR, no. (%) . | Samples tested before PTLD, no. . | Samples above cut-off value in Q-PCR before PTLD, no. (%) . | Samples tested after PTLD, no. . | Samples above cut-off value in Q-PCR after PTLD, no. (%) . |
|---|---|---|---|---|---|---|
| PTLD LTx (n = 6) | 141 | 96 (68) | 64 | 50 (78) | 77 | 46 (60) |
| Non-PTLD LTx (n = 8) | 117 | 4 (3.4) | NA | NA | NA | NA |
| Total | 258 | 100 (39) | — | — | — | — |
| Patients . | Total samples tested, no. . | Samples above cut-off value in Q-PCR, no. (%) . | Samples tested before PTLD, no. . | Samples above cut-off value in Q-PCR before PTLD, no. (%) . | Samples tested after PTLD, no. . | Samples above cut-off value in Q-PCR after PTLD, no. (%) . |
|---|---|---|---|---|---|---|
| PTLD LTx (n = 6) | 141 | 96 (68) | 64 | 50 (78) | 77 | 46 (60) |
| Non-PTLD LTx (n = 8) | 117 | 4 (3.4) | NA | NA | NA | NA |
| Total | 258 | 100 (39) | — | — | — | — |
Percentage of the total samples above cut-off value in Q-PCR is based on more than 2000 EBV DNA copies per mL blood. The followingP values were determined: The total number of samples above cut-off value in PTLD patients versus non-PTLD patients:P < .0001; number of samples above cut-off value before diagnosis of PTLD versus number of samples above cut-off value in non-PTLD patients: P < .0001; and number of samples above cut-off value before diagnosis of PTLD versus number of samples above cut-off value after diagnosis of PTLD patients: P< .02. NA indicates not applicable.