Table 1. Main features of the patients... | American Society of Hematology

Table 1.

Main features of the patients studied

Family (patients in the family)	Platelet count × 10⁹/L mean (range)	MPV fL mean (range)	Clinics^*(symptomatic patients)	GPIb/IX/V complex^†	Bolzano mutation
TP-1 (8)	69	14.0	P, E, M (4)	Defective	Yes
Figure 1	(50-82)	(13.7-14.5)
TP-2 (9)	88	12.9	P, E (6)	Defective	Yes
Figure 1	(21-127)	(12.2-13.6)
TP-3 (2)	94	11.7	E (2)	Defective	Yes
	(77-111)	(11.5-11.9)
TP-4 (2)	74	12.7	M (1)	nd	Yes
	(68-80)	(12.3-13.2)
TP-5 (3)	49	16.1	P (1)	Normal	No
	(22-82)	(14.0-17.2)
TP-6 (7)	140	11.6	No	Defective	No
	(100-178)	(11.2-12.3)
TP-7 (3)	90	11.4	E (2)	Normal	No
	(68-135)	(10.4-11.9)
TP-8 (3)	58	13.9	E, M (3)	Defective	Yes
	(42-87)	(12.1-14.3)
TP-9 (2)	45	12.9	P, E (2)	nd	Yes
	(37-53)	(12.7-13.1)
TP-10 (3)	119	11.4	No	Defective	No
	(109-133)	(10.7-11.9)
TP-11 (2)	143	14.1	No	Defective	No
	(128-158)	(13.8-14.5)
TP-12 (2)	120	11.5	E (1)	Defective	No
	(116-125)	(11.2-11.8)

Family (patients in the family)	Platelet count × 10⁹/L mean (range)	MPV fL mean (range)	Clinics^*(symptomatic patients)	GPIb/IX/V complex^†	Bolzano mutation
TP-1 (8)	69	14.0	P, E, M (4)	Defective	Yes
Figure 1	(50-82)	(13.7-14.5)
TP-2 (9)	88	12.9	P, E (6)	Defective	Yes
Figure 1	(21-127)	(12.2-13.6)
TP-3 (2)	94	11.7	E (2)	Defective	Yes
	(77-111)	(11.5-11.9)
TP-4 (2)	74	12.7	M (1)	nd	Yes
	(68-80)	(12.3-13.2)
TP-5 (3)	49	16.1	P (1)	Normal	No
	(22-82)	(14.0-17.2)
TP-6 (7)	140	11.6	No	Defective	No
	(100-178)	(11.2-12.3)
TP-7 (3)	90	11.4	E (2)	Normal	No
	(68-135)	(10.4-11.9)
TP-8 (3)	58	13.9	E, M (3)	Defective	Yes
	(42-87)	(12.1-14.3)
TP-9 (2)	45	12.9	P, E (2)	nd	Yes
	(37-53)	(12.7-13.1)
TP-10 (3)	119	11.4	No	Defective	No
	(109-133)	(10.7-11.9)
TP-11 (2)	143	14.1	No	Defective	No
	(128-158)	(13.8-14.5)
TP-12 (2)	120	11.5	E (1)	Defective	No
	(116-125)	(11.2-11.8)

P, petechias; E, epistaxis; M, mucosal bleeding; No, no clinical findings.

Defective means a reduction detected by flow cytometry; nd, nondetermined.