Comparison of HTLV-I tax sequences within pedigree with the prototypic strain ATK-1
| . | Sex . | Nucleotide change at position . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 7464 . | 7496 . | 7743 . | 7934 . | 7942 . | 7953 . | 8140 . | 8283 . | 8294 . | 8368 . | ||
| ATK-1 | G (W) | G (A) | G (G) | T (L) | C (T) | A (Q) | T (F) | A (N) | C (P) | G | |
| HAM 9 | F | G (R) | |||||||||
| Son of HAM 9 | M | G (R) | |||||||||
| HAM 10 | F | G (S) | |||||||||
| Son of HAM 10 | M | G (S) | |||||||||
| HAM 19 | M | A | |||||||||
| Wife of HAM 19 | F | A | |||||||||
| HAM 24 | F | C (L) | C (F) | ||||||||
| Sister of HAM 24 | F | C (L) | C (F) | ||||||||
| HAM 34 | F | A (T) | |||||||||
| Sister of HAM 34 (1) | F | A (T) | |||||||||
| Sister of HAM 34 (2) | F | A (T) | |||||||||
| HAM 39 | F | T (T) | |||||||||
| Husband of HAM 39 | M | T (T) | |||||||||
| ATL 36 | M | A (STOP) | A (D) | T (S) | |||||||
| Mother of ATL 36 | F | No change | A (D) | T (S) | |||||||
| Sister of ATL 36 | F | No change | A (D) | T (S) | |||||||
| . | Sex . | Nucleotide change at position . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 7464 . | 7496 . | 7743 . | 7934 . | 7942 . | 7953 . | 8140 . | 8283 . | 8294 . | 8368 . | ||
| ATK-1 | G (W) | G (A) | G (G) | T (L) | C (T) | A (Q) | T (F) | A (N) | C (P) | G | |
| HAM 9 | F | G (R) | |||||||||
| Son of HAM 9 | M | G (R) | |||||||||
| HAM 10 | F | G (S) | |||||||||
| Son of HAM 10 | M | G (S) | |||||||||
| HAM 19 | M | A | |||||||||
| Wife of HAM 19 | F | A | |||||||||
| HAM 24 | F | C (L) | C (F) | ||||||||
| Sister of HAM 24 | F | C (L) | C (F) | ||||||||
| HAM 34 | F | A (T) | |||||||||
| Sister of HAM 34 (1) | F | A (T) | |||||||||
| Sister of HAM 34 (2) | F | A (T) | |||||||||
| HAM 39 | F | T (T) | |||||||||
| Husband of HAM 39 | M | T (T) | |||||||||
| ATL 36 | M | A (STOP) | A (D) | T (S) | |||||||
| Mother of ATL 36 | F | No change | A (D) | T (S) | |||||||
| Sister of ATL 36 | F | No change | A (D) | T (S) | |||||||
Nucleotide changes at 7897, 7959, 8208, and 8344 are not shown because they are subgroup-specific changes. Prefix of the patient number HAM, ATL represent the disease status HAM/TSP and ATL, respectively. Amino acid of Tax is shown in parentheses.