Table 1.

Patient and disease characteristics

86 
Median age, y (range) 52 (22-70)  
Sex 52 M, 34 F 
Diagnosis and status at transplantation  
 AML/MDS 43 
  CR1 1  
  Untreated 1st relapse 10  
  Remission ≥ CR2 5  
  Refractory 27  
 CML 27  
  CR1 
  Transformed 21  
 ALL/lymphoma 16  
  Remission ≥ CR2 1  
  Refractory 15  
Median no. prior therapies (range) 3 (0-8)  
Median time to transplantation, d (range) 553 (27-6627)  
Prior transplantation 24 
 Autologous 16  
 Allogeneic different donor 
 Allogeneic same donor 3  
Donor type  
 6 of 6 Matched related 39  
 5 of 6 Mismatched related 7  
 6 of 6 Matched unrelated 40  
Stem cell source  
 Bone marrow 52 
 Peripheral blood 34  
CMV Status  
 Neg/neg 
Donor/recipient sex  
 Donor F/recipient M 23  
 Donor F/recipient F 19  
 Other 44  
Preparative regimen  
 Fludarabine/melphalan 180 66 
 Fludarabine/melphalan 140 12  
 Cladribine/melphalan 180 8  
GVHD prophylaxis  
 Tacrolimus/methotrexate 81 
 Other 
86 
Median age, y (range) 52 (22-70)  
Sex 52 M, 34 F 
Diagnosis and status at transplantation  
 AML/MDS 43 
  CR1 1  
  Untreated 1st relapse 10  
  Remission ≥ CR2 5  
  Refractory 27  
 CML 27  
  CR1 
  Transformed 21  
 ALL/lymphoma 16  
  Remission ≥ CR2 1  
  Refractory 15  
Median no. prior therapies (range) 3 (0-8)  
Median time to transplantation, d (range) 553 (27-6627)  
Prior transplantation 24 
 Autologous 16  
 Allogeneic different donor 
 Allogeneic same donor 3  
Donor type  
 6 of 6 Matched related 39  
 5 of 6 Mismatched related 7  
 6 of 6 Matched unrelated 40  
Stem cell source  
 Bone marrow 52 
 Peripheral blood 34  
CMV Status  
 Neg/neg 
Donor/recipient sex  
 Donor F/recipient M 23  
 Donor F/recipient F 19  
 Other 44  
Preparative regimen  
 Fludarabine/melphalan 180 66 
 Fludarabine/melphalan 140 12  
 Cladribine/melphalan 180 8  
GVHD prophylaxis  
 Tacrolimus/methotrexate 81 
 Other 

y indicates years; M, male; F, female; AML, acute myelogenous leukemia; MDS, myelodysplastic syndromes; CR, chronic phase; CML, chronic myelogenous leukemia; ALL, acute lymphoblastic leukemia; d, days; CMV, cytomegalovirus; Neg, negative; GVHD, graft-versus-host disease.

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