Characteristics of patients with the Flt3/ITD
| Registration no. . | Age (y) . | WBC (×103) . | Induction regimen . | Remission . | Relapse ? . | Alive ? . | FAB class . | Karyotype . | Postinduction treatment . | Duplication size (bp) . |
|---|---|---|---|---|---|---|---|---|---|---|
| 48846 | 17.3 | 73.8 | STD | Yes | No | Yes | M2 | NL | Chemo | 30 |
| 59237 | 11.7 | 436 | INT | No | Yes | Yes | M4 | NL | Allo × 2 | 69 |
| 59719 | 3.9 | 240.2 | INT | No | Yes | Yes | M2 | ND | Allo | 21 |
| 47604 | 3.1 | 43.7 | STD | No | Yes | No | M2 | ND | Allo | 33 |
| 51207 | 6.3 | 52.6 | INT | Yes | Yes | No | M4 | NL | Chemo | 27 |
| 51181 | 9.5 | 345.8 | STD | Yes | Yes | No | M4 | Inv 16 | Chemo | 48 |
| 53588 | 14.7 | 4.9 | INT | No | Yes | No | M3 | t (15;17) | Auto | 39 |
| 52416 | 3.6 | 9.4 | INT | Yes | Yes | No | M3 | t (15;17) | Auto | 45 |
| 53177 | 15.5 | 9.4 | STD | No | Yes | No | M2 | NL | Allo | 24 |
| 56586 | 17.8 | 453.1 | STD | Yes | Yes | No | M2 | del 14 (q21;q24) | Auto | 24 |
| 47053 | 12 | 410 | STD | No | NLM | No | M1 | Trisomy 8 | Chemo | 39 |
| 49447 | 8.1 | 42.7 | STD | Yes | NLM | No | M1 | del 13 (q12;q22) | Allo | 174 |
| 52454 | 7.8 | 246 | STD | No | NLM | No | M4 | NL | Chemo | 54 + 64-150 |
| 57258 | 8.3 | 165 | INT | No | NLM | No | M0 | 11q23 | None | 54 + 154-150 |
| 58340 | 18.7 | 7.9 | INT | Death | NLM | No | M2 | t (8;21) | Not applicable | 48 |
| Registration no. . | Age (y) . | WBC (×103) . | Induction regimen . | Remission . | Relapse ? . | Alive ? . | FAB class . | Karyotype . | Postinduction treatment . | Duplication size (bp) . |
|---|---|---|---|---|---|---|---|---|---|---|
| 48846 | 17.3 | 73.8 | STD | Yes | No | Yes | M2 | NL | Chemo | 30 |
| 59237 | 11.7 | 436 | INT | No | Yes | Yes | M4 | NL | Allo × 2 | 69 |
| 59719 | 3.9 | 240.2 | INT | No | Yes | Yes | M2 | ND | Allo | 21 |
| 47604 | 3.1 | 43.7 | STD | No | Yes | No | M2 | ND | Allo | 33 |
| 51207 | 6.3 | 52.6 | INT | Yes | Yes | No | M4 | NL | Chemo | 27 |
| 51181 | 9.5 | 345.8 | STD | Yes | Yes | No | M4 | Inv 16 | Chemo | 48 |
| 53588 | 14.7 | 4.9 | INT | No | Yes | No | M3 | t (15;17) | Auto | 39 |
| 52416 | 3.6 | 9.4 | INT | Yes | Yes | No | M3 | t (15;17) | Auto | 45 |
| 53177 | 15.5 | 9.4 | STD | No | Yes | No | M2 | NL | Allo | 24 |
| 56586 | 17.8 | 453.1 | STD | Yes | Yes | No | M2 | del 14 (q21;q24) | Auto | 24 |
| 47053 | 12 | 410 | STD | No | NLM | No | M1 | Trisomy 8 | Chemo | 39 |
| 49447 | 8.1 | 42.7 | STD | Yes | NLM | No | M1 | del 13 (q12;q22) | Allo | 174 |
| 52454 | 7.8 | 246 | STD | No | NLM | No | M4 | NL | Chemo | 54 + 64-150 |
| 57258 | 8.3 | 165 | INT | No | NLM | No | M0 | 11q23 | None | 54 + 154-150 |
| 58340 | 18.7 | 7.9 | INT | Death | NLM | No | M2 | t (8;21) | Not applicable | 48 |
Insertions of 6 and 15 base pairs upstream of the duplicated region.
WBC = white blood cell count; STD = standard timing; INT = intensive timing; NLM = nonleukemic mortality; NL = normal; ND = not determined; Allo = allogeneic bone marrow transplant; Auto = autologous bone marrow transplant; Chemo = chemotherapy.