Characterization of the 91 study patients with and without the Flt3/ITD
| Characteristics N = 91 . | Flt3/ITD-negative N = 76 (83.5%) . | Flt3/ITD-positive N = 15 (16.5%) . | P value . |
|---|---|---|---|
| Median age (range) | 10.9 (0.2-17.9) | 8.3 (3.1-18.7) | .46 |
| Median WBC × 103/mm3 (range) | 28.4 (0.5-480) | 73.8 (4.9-453) | .05 |
| Remission rate (%) | 74% | 40% | .005 |
| Actuarial overall survival (%) at 8 years | 50% | 13% | .02 |
| Actuarial event-free survival (%) at 8 years | 44% | 7% | .002 |
| Characteristics N = 91 . | Flt3/ITD-negative N = 76 (83.5%) . | Flt3/ITD-positive N = 15 (16.5%) . | P value . |
|---|---|---|---|
| Median age (range) | 10.9 (0.2-17.9) | 8.3 (3.1-18.7) | .46 |
| Median WBC × 103/mm3 (range) | 28.4 (0.5-480) | 73.8 (4.9-453) | .05 |
| Remission rate (%) | 74% | 40% | .005 |
| Actuarial overall survival (%) at 8 years | 50% | 13% | .02 |
| Actuarial event-free survival (%) at 8 years | 44% | 7% | .002 |
Flt3/ITD = Flt3 internal tandem duplication; WBC = white blood cell count.