Table 2.

Results of the bcl-2–JH PCR analysis on day 50 and clinical outcome (n = 30)

Patient
number
CR/CRuPRSD/ProgProgression
at 12
months*
Peripheral blood PCR negative 17 10 1  
 With BM PCR negative 0  
 With BM PCR positive 1  
 With BM untested 0  
Peripheral blood PCR positive 13 
Patient
number
CR/CRuPRSD/ProgProgression
at 12
months*
Peripheral blood PCR negative 17 10 1  
 With BM PCR negative 0  
 With BM PCR positive 1  
 With BM untested 0  
Peripheral blood PCR positive 13 

Only 30 of 32 patients with bcl-2–JH rearrangement at diagnosis were evaluated on day 50.

*

2-tailed Fisher exact test for comparison of PCR analysis on day 50 and clinical outcome at 12 months (P < .0001).

All patients who were PCR positive in peripheral blood were also PCR positive in bone marrow, except 2 untested in bone marrow.

2-tailed Fisher exact test for comparison of PCR analysis on day 50 and clinical outcome on day 78 (P < .0001).

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