Table 1. Differential repopulating... | American Society of Hematology

Table 1.

Differential repopulating activity of G₀/G₁ and S/G₂/M cells present in 5-day cultures of CD34⁺ cord blood cells

Experiment no.	G₀/G₁			S/G₂/M
	Cells per mouse^* (×10⁶)	Fraction of positive mice		Cells per mouse^*(×10⁶)	Fraction of positive mice
	Cells per mouse^* (×10⁶)	L⁺ + M⁺ (% human cells)^†	L⁺ ± M⁺	Cells per mouse^*(×10⁶)	L⁺ + M⁺	L⁺ ± M⁺
1	1.5	2/6 (0.6, 0.3)	6/6	0.73	0/6	4/6
2	1.0	6/6 (1.3, 10.9, 0.7, 1.5, 0.6, 1.5)	6/6	0.65	0/6	0/6
3	0.78	3/5 (1.1, 0.2, 0.6)	5/5	0.46	0/5	0/5

Experiment no.	G₀/G₁			S/G₂/M
	Cells per mouse^* (×10⁶)	Fraction of positive mice		Cells per mouse^*(×10⁶)	Fraction of positive mice
	Cells per mouse^* (×10⁶)	L⁺ + M⁺ (% human cells)^†	L⁺ ± M⁺	Cells per mouse^*(×10⁶)	L⁺ + M⁺	L⁺ ± M⁺
1	1.5	2/6 (0.6, 0.3)	6/6	0.73	0/6	4/6
2	1.0	6/6 (1.3, 10.9, 0.7, 1.5, 0.6, 1.5)	6/6	0.65	0/6	0/6
3	0.78	3/5 (1.1, 0.2, 0.6)	5/5	0.46	0/5	0/5

More than 90% of all cells in each fraction from the entire culture were injected into 6 irradiated NOD/SCID mice in each experiment.

†

% of human CD45/CD71⁺ cells in the bone marrow of those mice found to be positive 6 weeks after transplant (L⁺= at least 5 of 20 000 cells were human CD34⁻CD19/20⁺, M⁺ = at least 5 of 20 000 cells were human CD45/71⁺CD15/66b⁺cells).

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