Gene-modified cell characteristics
| Control . | Expected value . | Observed values, median . | Observed values, range . |
|---|---|---|---|
| Transduction efficiency before G418 selection, % | — | 8.3 | 1.5 -19.7 |
| Viability after thawing, % | > 60 | 77.4 | 60 -92 |
| Ratio, GMC/PBMC input | — | 6.1 | 1.5 -15.4 |
| GCV inhibition, % | > 80 | 87 | 80 -93 |
| CD3+ cells, % | > 50 | 90.5 | 71.4 -97.2 |
| Control . | Expected value . | Observed values, median . | Observed values, range . |
|---|---|---|---|
| Transduction efficiency before G418 selection, % | — | 8.3 | 1.5 -19.7 |
| Viability after thawing, % | > 60 | 77.4 | 60 -92 |
| Ratio, GMC/PBMC input | — | 6.1 | 1.5 -15.4 |
| GCV inhibition, % | > 80 | 87 | 80 -93 |
| CD3+ cells, % | > 50 | 90.5 | 71.4 -97.2 |
The expected value indicates the quality control criteria.