Comparison of primary cutaneous ALCL with lymphomatoid papulosis
| Features . | Cutaneous ALCL . | Lymphomatoid papulosis . |
|---|---|---|
| Gross morphology | Nodules | Papules |
| Histology | Clusters/sheets of CD30+ blasts, Hodgkin-like cellular background | Few CD30+ blasts, variable number of cerebriform T cells, many inflammatory cells |
| Distribution | Localized | Regional or generalized |
| Extracutaneous spread | Occasional | Very rare |
| Self-healing | Variable | Always |
| Features . | Cutaneous ALCL . | Lymphomatoid papulosis . |
|---|---|---|
| Gross morphology | Nodules | Papules |
| Histology | Clusters/sheets of CD30+ blasts, Hodgkin-like cellular background | Few CD30+ blasts, variable number of cerebriform T cells, many inflammatory cells |
| Distribution | Localized | Regional or generalized |
| Extracutaneous spread | Occasional | Very rare |
| Self-healing | Variable | Always |
Adapted from Kadin.150