Table 6.

Summary of Epstein-Barr virus loads and tumor response in post-transplantation lymphoproliferative disease patients following rituximab therapy

PTLD patients6-150Number of EBV genomes per 106 PBMCsTumor response
Pretreatment5 weeks post-treatment
P1 10 711 46 Progressed 
P2 15 073 222 Progressed 
P4 19 579 3 368 Responded 
P6 2 930 6-151 
P7 72 537 56-152 Progressed 
PTLD patients6-150Number of EBV genomes per 106 PBMCsTumor response
Pretreatment5 weeks post-treatment
P1 10 711 46 Progressed 
P2 15 073 222 Progressed 
P4 19 579 3 368 Responded 
P6 2 930 6-151 
P7 72 537 56-152 Progressed 

PTLD indicates post-transplantation lymphoproliferative disease; PMBC, peripheral blood mononuclear cell.

F6-150

All patients had CD20+, EBV+ B-cell lymphoma.

F6-151

Patient P6 was inevaluable for tumor response because radiation therapy was used as primary treatment and the rituximab was used as consolidation.

F6-152

This specimen was obtained 5 months post-treatment.

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