Table 1. Host genes that affect... | American Society of Hematology

Table 1.

Host genes that affect susceptibility to Friend virus–induced disease

	Gene	Function
Group 1: interference with retroviral infection	Fv4	Blocks retroviral cell surface receptors
	Fv1	Interferes with retroviral life cycle
Group 2: altered immune response	Fv3	Susceptibility to Friend virus-induced immunosuppression
	Rfv1, Rfv2	H2-linked determinants of immune response
	Rfv3	Non–H2-linked determinant of immune response
Group 3: regulators of erythroid cell proliferation and differentiation	Fv5	Determines anemia vs polycythemia
	Kit, Mgf	Required for normal erythropoiesis
	Fv2	Determines proliferative response to gp55

	Gene	Function
Group 1: interference with retroviral infection	Fv4	Blocks retroviral cell surface receptors
	Fv1	Interferes with retroviral life cycle
Group 2: altered immune response	Fv3	Susceptibility to Friend virus-induced immunosuppression
	Rfv1, Rfv2	H2-linked determinants of immune response
	Rfv3	Non–H2-linked determinant of immune response
Group 3: regulators of erythroid cell proliferation and differentiation	Fv5	Determines anemia vs polycythemia
	Kit, Mgf	Required for normal erythropoiesis
	Fv2	Determines proliferative response to gp55