Quantification of the area of lamellae after platelet activation by CRP
.
Lamellar area ± SD (μm2)
.
Human
Control
6.38 ± 4.39 (n = 74)
+50 nmol/L wortmannin
0.22 ± 0.02 (n = 81)
Mouse
Gelsolin+/+
3.65 ± 2.45 (n = 99)
Gelsolin−/−
0.55 ± 0.46 (n = 128)
.
Lamellar area ± SD (μm2)
.
Human
Control
6.38 ± 4.39 (n = 74)
+50 nmol/L wortmannin
0.22 ± 0.02 (n = 81)
Mouse
Gelsolin+/+
3.65 ± 2.45 (n = 99)
Gelsolin−/−
0.55 ± 0.46 (n = 128)
Platelets stimulated as in Figure 5 were examined by video microscopy. Images were taken after 10 minutes of activation, and lamellar areas were measured in video frames using the NIH image analysis program. Results shown are the total of 3 experiments for each condition of activation.