Table 3.

Immunophenotipic analyses (percentages of cells) in 2 groups of newborns

MarkerSR (n = 20)UC (n = 14)Statistical significance (P value)
CD4 52.1 ± 4.9 59 ± 4.6 .069 
CD8 22.1 ± 5.0 16.1 ± 3.4 < .0001  
CD4/CD8 ratio 2.7 ± 1.1 3.8 ± 0.9 .00015 
CD4/RA/62 74.7 ± 8.9 89.7 ± 3.7 < .0001 
CD4/RO 24.9 ± 9.6 10.3 ± 3.3 < .0001 
CD8/RA/LFAlow 58.9 ± 15.3 77.7 ± 3.8 .0033 
CD8/RA/LFAhigh 22.1 ± 4.3 9.6 ± 4.1 .0027 
CD8/38dim 49.3 ± 13.9 79.7 ± 3.1 < .0001 
CD8/38bright 24.2 ± 11.1 1.8 ± 1.3 <.0001  
CD3 DN 9.3 ± 2.6 3.3 ± 1.1 < .0001  
CD3 DN/44 8.8 ± 2.7 3.1 ± 0.9 <.0001 
MarkerSR (n = 20)UC (n = 14)Statistical significance (P value)
CD4 52.1 ± 4.9 59 ± 4.6 .069 
CD8 22.1 ± 5.0 16.1 ± 3.4 < .0001  
CD4/CD8 ratio 2.7 ± 1.1 3.8 ± 0.9 .00015 
CD4/RA/62 74.7 ± 8.9 89.7 ± 3.7 < .0001 
CD4/RO 24.9 ± 9.6 10.3 ± 3.3 < .0001 
CD8/RA/LFAlow 58.9 ± 15.3 77.7 ± 3.8 .0033 
CD8/RA/LFAhigh 22.1 ± 4.3 9.6 ± 4.1 .0027 
CD8/38dim 49.3 ± 13.9 79.7 ± 3.1 < .0001 
CD8/38bright 24.2 ± 11.1 1.8 ± 1.3 <.0001  
CD3 DN 9.3 ± 2.6 3.3 ± 1.1 < .0001  
CD3 DN/44 8.8 ± 2.7 3.1 ± 0.9 <.0001 

SR = healthy HIV-uninfected children of HIV-infected mothers (seroreverters); UC = healthy children of HIV-negative women (uninfected controls); DN = double negatives; LFA = leukocyte function-associated antigen.

Mean values ± standard deviations are shown.