Aspirin's effect on serum TxB2, 2,3-dinor TxB2 and 2,3-dinor-6-keto PGF1α levels in apoE−/− and LDLR−/− mice (n = 4 for each group) at baseline (B) and after 1 week on aspirin (A)
| . | . | Serum TxB2(ng/mL) . | 2,3-dinor TxB2 (ng/mg creatinine) . | 2,3-dinor-6-keto PGF1α (ng/mg creatinine) . |
|---|---|---|---|---|
| ApoE−/− | B | 175 ± 20 | 13 ± 2 | 1.5 ± 0.20 |
| A | 10 ± 1.53-150 | 1.5 ± 0.53-150 | 0.74 ± 0.183-150 | |
| LDLR−/− | B | 180 ± 18 | 110 ± 10 | 3.8 ± 0.25 |
| A | 9 ± 1.63-150 | 10 ± 2.53-150 | 1.68 ± 0.203-150 |
| . | . | Serum TxB2(ng/mL) . | 2,3-dinor TxB2 (ng/mg creatinine) . | 2,3-dinor-6-keto PGF1α (ng/mg creatinine) . |
|---|---|---|---|---|
| ApoE−/− | B | 175 ± 20 | 13 ± 2 | 1.5 ± 0.20 |
| A | 10 ± 1.53-150 | 1.5 ± 0.53-150 | 0.74 ± 0.183-150 | |
| LDLR−/− | B | 180 ± 18 | 110 ± 10 | 3.8 ± 0.25 |
| A | 9 ± 1.63-150 | 10 ± 2.53-150 | 1.68 ± 0.203-150 |
Results are expressed as mean ± SEM (
P< 0.001).