Hemodynamic characteristics of A23187-activated venules
| Genotype donor platelets . | Treatment . | Genotype recipient . | Venular diameter (μm) . | Centerline velocity (mm/s) . | Shear rate (s−1) . |
|---|---|---|---|---|---|
| WT | — | WT | 191 ± 14 | 3.3 ± 0.46 | 93 ± 17 |
| P−/− | — | P−/− | 188 ± 11 | 3.31 ± 0.42 | 92 ± 17 |
| vWF−/− | — | vWF−/− | 174 ± 12 | 3.22 ± 0.49 | 98 ± 18 |
| β3−/− | — | β3−/− | 157 ± 20 | 2.66 ± 0.61 | 84 ± 14 |
| WT | Anti–PSGL-1 | WT | 174 ± 13 | 2.88 ± 0.19 | 84 ± 5 |
| WT | Anti–PECAM-1 | WT | 165 ± 18 | 2.9 ± 0.28 | 91 ± 16 |
| P−/− | — | GPIb−/− | 177 ± 14 | 2.97 ± 0.25 | 87 ± 13 |
| mGPIb−/−;TghGPIb | — | P−/− | 185 ± 16 | 3 ± 0.37 | 81 ± 4 |
| mGPIb−/−;TghGPIb | Mocarhagin | P−/− | 192 ± 2 | 2.86 ± 0.23 | 75 ± 6 |
| WT | Mocarhagin | P−/− | 171 ± 12 | 2.35 ± 0.31 | 74 ± 17 |
| Genotype donor platelets . | Treatment . | Genotype recipient . | Venular diameter (μm) . | Centerline velocity (mm/s) . | Shear rate (s−1) . |
|---|---|---|---|---|---|
| WT | — | WT | 191 ± 14 | 3.3 ± 0.46 | 93 ± 17 |
| P−/− | — | P−/− | 188 ± 11 | 3.31 ± 0.42 | 92 ± 17 |
| vWF−/− | — | vWF−/− | 174 ± 12 | 3.22 ± 0.49 | 98 ± 18 |
| β3−/− | — | β3−/− | 157 ± 20 | 2.66 ± 0.61 | 84 ± 14 |
| WT | Anti–PSGL-1 | WT | 174 ± 13 | 2.88 ± 0.19 | 84 ± 5 |
| WT | Anti–PECAM-1 | WT | 165 ± 18 | 2.9 ± 0.28 | 91 ± 16 |
| P−/− | — | GPIb−/− | 177 ± 14 | 2.97 ± 0.25 | 87 ± 13 |
| mGPIb−/−;TghGPIb | — | P−/− | 185 ± 16 | 3 ± 0.37 | 81 ± 4 |
| mGPIb−/−;TghGPIb | Mocarhagin | P−/− | 192 ± 2 | 2.86 ± 0.23 | 75 ± 6 |
| WT | Mocarhagin | P−/− | 171 ± 12 | 2.35 ± 0.31 | 74 ± 17 |