Substrates of BCR-ABL
| Protein . | Function . | Reference . |
|---|---|---|
| P62DOK | Adapter | 74 |
| Crkl | Adapter | 73 |
| Crk | Adapter | 13 |
| Shc | Adapter | 75 |
| Talin | Cytoskeleton/cell membrane | 76 |
| Paxillin | Cytoskeleton/cell membrane | 77 |
| Fak | Cytoskeleton/cell membrane | 78 |
| Fes | Myeloid differentiation | 79 |
| Ras-GAP | Ras-GTPase | 80 |
| GAP-associated proteins | Ras activation? | 214 |
| PLCγ | Phospholipase | 80 |
| PI3 kinase (p85 subunit) | Serine kinase | 127 |
| Syp | Cytoplasmic phosphatase | 83 |
| Bap-1 | 14-3-3 protein | 24 |
| Cbl | Unknown | 81 |
| Vav | Hematopoietic differentiation | 82 |
| Protein . | Function . | Reference . |
|---|---|---|
| P62DOK | Adapter | 74 |
| Crkl | Adapter | 73 |
| Crk | Adapter | 13 |
| Shc | Adapter | 75 |
| Talin | Cytoskeleton/cell membrane | 76 |
| Paxillin | Cytoskeleton/cell membrane | 77 |
| Fak | Cytoskeleton/cell membrane | 78 |
| Fes | Myeloid differentiation | 79 |
| Ras-GAP | Ras-GTPase | 80 |
| GAP-associated proteins | Ras activation? | 214 |
| PLCγ | Phospholipase | 80 |
| PI3 kinase (p85 subunit) | Serine kinase | 127 |
| Syp | Cytoplasmic phosphatase | 83 |
| Bap-1 | 14-3-3 protein | 24 |
| Cbl | Unknown | 81 |
| Vav | Hematopoietic differentiation | 82 |