Results of the Cox proportional hazards model evaluating the prognostic importance of having two consecutive positive traumatic lumbar punctures (TLP++) in patients whose final CNS classification was CNS 1 or TLP++*
| Adverse feature . | Hazard ratio . | 95% CI . | P value . |
|---|---|---|---|
| TLP++ | 2.39 | (1.36, 4.20) | .003 |
| NCI high-risk group | 2.04 | (1.29, 3.24) | .002 |
| DNA index < 1.16 or > 1.6 | 1.53 | (0.83, 2.80) | .17 |
| T-cell ALL | 1.51 | (0.85, 2.67) | .16 |
| Adverse feature . | Hazard ratio . | 95% CI . | P value . |
|---|---|---|---|
| TLP++ | 2.39 | (1.36, 4.20) | .003 |
| NCI high-risk group | 2.04 | (1.29, 3.24) | .002 |
| DNA index < 1.16 or > 1.6 | 1.53 | (0.83, 2.80) | .17 |
| T-cell ALL | 1.51 | (0.85, 2.67) | .16 |
CNS indicates central nervous system; CI, confidence interval; NCI, National Cancer Institute; ALL, acute lymphoblastic leukemia.
Stratified for treatment protocol and simultaneously adjusting for NCI/Rome criteria, DNA index, and immunophenotype.