Table 1. Effect of the L-selectin... | American Society of Hematology

Table 1.

Effect of the L-selectin shedding inhibitor KD-IX-73-4 on the L-selectin expression of neutrophils treated with several NSAIDs

	−KD-IX-73-4	+KD-IX-73-4 (20 μmol/L)
Medium	100	124 ± 2
Piroxicam	92 ± 4	109 ± 3
Indomethacin	70 ± 10^*	128 ± 19^‡
Aspirin	60 ± 10^†	105 ± 7^‡
Diclofenac	40 ± 11^†	96 ± 5^‡
Mefenamic acid	32 ± 23^†	88 ± 3^‡
Aceclofenac	29 ± 13^†	91 ± 7^‡
Flufenamic acid	23 ± 2^†	88 ± 10^‡

	−KD-IX-73-4	+KD-IX-73-4 (20 μmol/L)
Medium	100	124 ± 2
Piroxicam	92 ± 4	109 ± 3
Indomethacin	70 ± 10^*	128 ± 19^‡
Aspirin	60 ± 10^†	105 ± 7^‡
Diclofenac	40 ± 11^†	96 ± 5^‡
Mefenamic acid	32 ± 23^†	88 ± 3^‡
Aceclofenac	29 ± 13^†	91 ± 7^‡
Flufenamic acid	23 ± 2^†	88 ± 10^‡

NSAIDs = nonsteroidal anti-inflammatory drugs.

Values are the mean ± SD of relative mean fluorescence intensity of 3 independent experiments.

P < .05 versus medium by paired t test.

P < .01 versus medium by paired t test.

P < .01 versus the same NSAIDs alone by pairedt test.