Characteristics of the study population
| Case . | Age (yr)/sex . | Bony disease at diagnosis . | Serology . | Status at BMT . | Bisphosphonate pre-BMT . |
|---|---|---|---|---|---|
| 1 | 54/M | Yes | Urinary kappa light chains | 1st CR | Yes |
| 2 | 52/F | Yes | Serum IgA lambda | 1st plateau | No |
| 3 | 63/F | Yes | Urinary lambda light chains | 1st plateau | Yes |
| 4 | 57/M | Yes | Serum IgA kappa | 1st plateau | No |
| 5 | 40/F | Yes | Serum IgG kappa | 1st plateau | No |
| 6 | 48/M | Yes | Serum IgA kappa (also small IgG) | 1st CR | Yes |
| 7 | 58/F | Yes | Serum IgA kappa | 1st CR | Yes |
| 8 | 68/F | Yes | Serum IgG lambda | 1st plateau | Yes |
| 9 | 44/M | No | Serum IgG kappa | 2nd response | No |
| 10 | 58/F | Yes | Urinary lambda light chains | 1st CR | Yes |
| 11 | 61/F | Yes | Nonsecretory | 1st CR | No |
| 12 | 52/F | Yes | Serum IgG kappa | 1st plateau | Yes |
| 13 | 60/F | Yes | Serum IgG lambda | 1st plateau | Yes |
| 14 | 40/M | Yes | Nonsecretory | 1st CR | No |
| 15 | 63/F | Yes | Nonsecretory | 1st CR | No |
| 16 | 64/M | Yes | Serum IgG kappa | 1st plateau | Yes |
| 17 | 59/M | Yes | Nonsecretory | 1st CR | Yes |
| 18 | 53/M | No | Urinary lambda light chains | 2nd response | No |
| 19 | 44/M | No | Serum IgG lambda | 1st plateau | No |
| 20 | 50/M | No | Serum IgG kappa | 1st plateau | Yes |
| 21 | 51/M | Yes | Urinary kappa light chains | 1st plateau | Yes |
| 22 | 56/M | No | Serum IgA lambda | 1st CR | No |
| 23 | 61/M | No | Serum IgA kappa | 1st CR | No |
| 24 | 52/M | Yes | Serum IgG | 1st plateau | No |
| 25 | 52/F | No | Serum IgG lambda | 1st plateau | No |
| 26 | 53/F | Yes | Urinary lambda light chains | 1st CR | No |
| 27 | 52/M | Yes | Serum IgG kappa | 1st plateau | Yes |
| 28 | 41/M | Yes | Serum IgG kappa | 1st plateau | No |
| 29 | 55/M | Yes | Serum IgA kappa | 2nd CR | Yes |
| 30 | 51/F | Yes | Serum IgG kappa | 1st CR | Yes |
| 31 | 61/M | Yes | Serum IgA lambda | 1st plateau | Yes |
| 32 | 46/M | No | Serum IgG lambda | 1st CR | Yes |
| Case . | Age (yr)/sex . | Bony disease at diagnosis . | Serology . | Status at BMT . | Bisphosphonate pre-BMT . |
|---|---|---|---|---|---|
| 1 | 54/M | Yes | Urinary kappa light chains | 1st CR | Yes |
| 2 | 52/F | Yes | Serum IgA lambda | 1st plateau | No |
| 3 | 63/F | Yes | Urinary lambda light chains | 1st plateau | Yes |
| 4 | 57/M | Yes | Serum IgA kappa | 1st plateau | No |
| 5 | 40/F | Yes | Serum IgG kappa | 1st plateau | No |
| 6 | 48/M | Yes | Serum IgA kappa (also small IgG) | 1st CR | Yes |
| 7 | 58/F | Yes | Serum IgA kappa | 1st CR | Yes |
| 8 | 68/F | Yes | Serum IgG lambda | 1st plateau | Yes |
| 9 | 44/M | No | Serum IgG kappa | 2nd response | No |
| 10 | 58/F | Yes | Urinary lambda light chains | 1st CR | Yes |
| 11 | 61/F | Yes | Nonsecretory | 1st CR | No |
| 12 | 52/F | Yes | Serum IgG kappa | 1st plateau | Yes |
| 13 | 60/F | Yes | Serum IgG lambda | 1st plateau | Yes |
| 14 | 40/M | Yes | Nonsecretory | 1st CR | No |
| 15 | 63/F | Yes | Nonsecretory | 1st CR | No |
| 16 | 64/M | Yes | Serum IgG kappa | 1st plateau | Yes |
| 17 | 59/M | Yes | Nonsecretory | 1st CR | Yes |
| 18 | 53/M | No | Urinary lambda light chains | 2nd response | No |
| 19 | 44/M | No | Serum IgG lambda | 1st plateau | No |
| 20 | 50/M | No | Serum IgG kappa | 1st plateau | Yes |
| 21 | 51/M | Yes | Urinary kappa light chains | 1st plateau | Yes |
| 22 | 56/M | No | Serum IgA lambda | 1st CR | No |
| 23 | 61/M | No | Serum IgA kappa | 1st CR | No |
| 24 | 52/M | Yes | Serum IgG | 1st plateau | No |
| 25 | 52/F | No | Serum IgG lambda | 1st plateau | No |
| 26 | 53/F | Yes | Urinary lambda light chains | 1st CR | No |
| 27 | 52/M | Yes | Serum IgG kappa | 1st plateau | Yes |
| 28 | 41/M | Yes | Serum IgG kappa | 1st plateau | No |
| 29 | 55/M | Yes | Serum IgA kappa | 2nd CR | Yes |
| 30 | 51/F | Yes | Serum IgG kappa | 1st CR | Yes |
| 31 | 61/M | Yes | Serum IgA lambda | 1st plateau | Yes |
| 32 | 46/M | No | Serum IgG lambda | 1st CR | Yes |
BMT, bone marrow transplant; CR, complete response; Ig, immunoglobulin.