Table 2.

HLA-B60–binding peptides derived from the 1-523 AA region of the UTY protein

AA position UTY proteinPeptideScore
164-172 KEIHLRLGL 704 000 
29-38 RESEEESVSL 640 000 
60-69 HEDGARTKT160 000 
164-173 KEIHLRLGLM 40 000 
41-49 EEREALGGM 20 000 
61-69 EDGARTKT20 000 
398-407 SDNWNGGQSL 20 000 
40-49 VEEREALGGM 20 000 
121-130 ADYWKNAAFL 20 000 
61-70 EDGARTKTLL 20 000 
32-40 EEESVSLTV 17 600 
31-40 SEEESVSLTV 17 600 
AA position UTY proteinPeptideScore
164-172 KEIHLRLGL 704 000 
29-38 RESEEESVSL 640 000 
60-69 HEDGARTKT160 000 
164-173 KEIHLRLGLM 40 000 
41-49 EEREALGGM 20 000 
61-69 EDGARTKT20 000 
398-407 SDNWNGGQSL 20 000 
40-49 VEEREALGGM 20 000 
121-130 ADYWKNAAFL 20 000 
61-70 EDGARTKTLL 20 000 
32-40 EEESVSLTV 17 600 
31-40 SEEESVSLTV 17 600 

The region between amino acids 1 and 523 of the UTY protein was screened for HLA-B60–binding peptides. Scores are predictions of half-time of dissociation to HLA-B60 molecules for the indicated peptides. Underlined amino acids are mutations compared to the UTX sequence.

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