Table 2. Skewness of the TCR BV... | American Society of Hematology

Table 2.

Skewness of the TCR BV repertoire in PNH and control individuals as determined by quadratic regression analysis

TCR family	Mean R-square value per TCR BV family		P value
TCR family	Controls^*	PNH patients	P value
BV1	0.89	0.81	NS
BV2	0.93	0.89	NS
BV3	0.91	0.79	NS
BV4	0.90	0.89	NS
BV5	0.92	0.89	NS
BV6	0.89	0.90	NS
BV7	0.92	0.78	0.03
BV8	0.91	0.82	0.03
BV9	0.91	0.76	0.02
BV11	0.87	0.79	0.02
BV12	0.91	0.77	0.01
BV13	0.94	0.87	NS
BV14	0.93	0.82	NS
BV15	0.78	0.77	NS
BV16	0.91	0.82	NS
BV17	0.93	0.84	0.03
BV18	0.94	0.85	0.04
BV21	0.89	0.87	NS
BV22	0.89	0.86	NS
BV23	0.91	0.75	NS
BV24	0.93	0.85	NS
Overall mean ± SD	0.91 ± 0.03	0.82 ± 0.03	<0.001

TCR family	Mean R-square value per TCR BV family		P value
TCR family	Controls^*	PNH patients	P value
BV1	0.89	0.81	NS
BV2	0.93	0.89	NS
BV3	0.91	0.79	NS
BV4	0.90	0.89	NS
BV5	0.92	0.89	NS
BV6	0.89	0.90	NS
BV7	0.92	0.78	0.03
BV8	0.91	0.82	0.03
BV9	0.91	0.76	0.02
BV11	0.87	0.79	0.02
BV12	0.91	0.77	0.01
BV13	0.94	0.87	NS
BV14	0.93	0.82	NS
BV15	0.78	0.77	NS
BV16	0.91	0.82	NS
BV17	0.93	0.84	0.03
BV18	0.94	0.85	0.04
BV21	0.89	0.87	NS
BV22	0.89	0.86	NS
BV23	0.91	0.75	NS
BV24	0.93	0.85	NS
Overall mean ± SD	0.91 ± 0.03	0.82 ± 0.03	<0.001

Healthy and transfused controls combined.

NS: not significant.