Table 5. Clinical severity of β-thal/HbE... | American Society of Hematology

Table 5.

Clinical severity of β-thal/HbE

Patient no.	Hgb (g/L)	HbF (%)	HbE (%)	Ferritin (μg/L)	Erythroid precursors undergoing apoptosis (%)^5-150
Patient no.	Hgb (g/L)	HbF (%)	HbE (%)	Ferritin (μg/L)	Annexin V	Hoechst
009 β⁰	85	15.1	71.4	1645	14.4	17.1
012 β⁰	103	15.2	76.3	201	11.7	8.9
013 β⁰	113	25.7	62.5	324	11.9	14.1
014 β⁰ Splx	46	19.9	67.2	4516	19.3	13.2
015 β⁰	54	17.5	67.4	2580	13.7	13.7
020 β⁰Splx	56	37.1	59.1	5445	14.9	6.5
025 β⁺	83	20.4	56.4	2170	10.9	—
025-1 β⁺	75	20.4	56.4	3274	11.5	—
043 β	83	26.9	68.9	318	15.7	—
044 β⁰Splx	44	35.7	55.7	6660	19.6	—
046 β⁰	61	33.3^5-151	51.2	447	15.1	—
049 β⁰Splx	44	51.5^5-151	48.0	978	6.9	—
051 β⁰	48	13.2	75.5	739	10.7	—
052 β⁰	98	3.6	95.1	244	12.7	—
054 β⁰	53	11.4^5-151	74.1	4765	6.9	—
055 β⁰	71	27.2^5-151	57.1	964	12.4	—

Patient no.	Hgb (g/L)	HbF (%)	HbE (%)	Ferritin (μg/L)	Erythroid precursors undergoing apoptosis (%)^5-150
Patient no.	Hgb (g/L)	HbF (%)	HbE (%)	Ferritin (μg/L)	Annexin V	Hoechst
009 β⁰	85	15.1	71.4	1645	14.4	17.1
012 β⁰	103	15.2	76.3	201	11.7	8.9
013 β⁰	113	25.7	62.5	324	11.9	14.1
014 β⁰ Splx	46	19.9	67.2	4516	19.3	13.2
015 β⁰	54	17.5	67.4	2580	13.7	13.7
020 β⁰Splx	56	37.1	59.1	5445	14.9	6.5
025 β⁺	83	20.4	56.4	2170	10.9	—
025-1 β⁺	75	20.4	56.4	3274	11.5	—
043 β	83	26.9	68.9	318	15.7	—
044 β⁰Splx	44	35.7	55.7	6660	19.6	—
046 β⁰	61	33.3^5-151	51.2	447	15.1	—
049 β⁰Splx	44	51.5^5-151	48.0	978	6.9	—
051 β⁰	48	13.2	75.5	739	10.7	—
052 β⁰	98	3.6	95.1	244	12.7	—
054 β⁰	53	11.4^5-151	74.1	4765	6.9	—
055 β⁰	71	27.2^5-151	57.1	964	12.4	—

Splx indicates splenectomy.

As assessed by the annexin V and Hoechst 33342 methods.

Determined by alkaline denaturation.