Variables in patients with β0thalassemia/hemoglobin E
Patient no. . | Hgb (g/L) . | MCV (fl) . | Retics (%) . | SI (μmol/L) . | TIBC (μmol/L) . | Tf sat (%) . | HbE (%) . | HbF (%) . | 51Cr RBC T½ (days) . | PITR3-150 . | RBC59Fe use (%) . |
---|---|---|---|---|---|---|---|---|---|---|---|
Mild cases | |||||||||||
1 | 80 | 66 | 4.2 | 21 | 45 | 46.2 | — | — | 10.5 | 2.5 | 49.0 |
2 | 103 | 69 | 1.2 | 15 | 29 | 51.0 | 50.44 | 37.68 | 19.5 | 2.8 | 30.0 |
3 | 85 | 62 | 1.1 | 33 | 35 | 93.7 | 75.80 | 13.67 | 20.7 | 2.0 | 43.0 |
4 | 94 | 68 | 2.0 | 30 | 32 | 93.6 | 61.75 | 22.76 | 13.5 | 3.7 | 37.2 |
5 | 72 | 69 | 1.4 | 15 | 26 | 56.5 | 45.45 | 27.06 | 16.8 | 4.5 | 27.8 |
6 | 123 | 73 | 0.8 | 20 | 32 | 67.4 | 33.94 | 34.50 | 21.0 | 3.3 | 27.0 |
Mean ± SD | 93 ± 18 | 67.8 ± 3.7 | 1.8 ± 1.2 | 22.3 ± 7.6 | 33.2 ± 6.6 | 68.1 ± 21.0 | 53.5 ± 16.0 | 27.1 ± 9.6 | 17.0 ± 4.3 | 3.1 ± 0.9 | 35.7 ± 9.0 |
Severe cases | |||||||||||
7 | 52 | 65 | 4.0 | 24 | 27 | 91.0 | 68.86 | 18.60 | 10.0 | 7.6 | — |
8 | 69 | 86 | 8.5 | 44 | 50 | 96.9 | 47.21 | 30.73 | 8.6 | 6.1 | 41.8 |
9 | 64 | 77 | 7.6 | 43 | 46 | 92.9 | 45.21 | 30.54 | 10.3 | 6.6 | 27.6 |
10 | 69 | 90 | 17.2 | 33 | 35 | 93.6 | 41.55 | 31.09 | 10.8 | 6.7 | 27.6 |
11 | 65 | 92 | 24.4 | 50 | 59 | 84.8 | 50.70 | 24.48 | 6.2 | 6.9 | 44.1 |
Mean ± SD | 64 ± 7 | 82.0 ± 11.1 | 12.3 ± 8.3 | 38.8 ± 10.3 | 43.4 ± 12.6 | 91.8 ± 4.5 | 50.7 ± 10.7 | 27.1 ± 5.5 | 9.2 ± 1.9 | 6.8 ± 0.5 | 35.3 ± 8.9 |
Pvalue | .01 | .04 | .05 | .02 | .15 | .04 | .76 | .99 | <.005 | <.0001 | .95 |
Normal | — | 84.9 ± 8.1 | 1.7 ± 1.6 | 20.6 ± 5.8 | 55.9 ± 7.2 | 35.8 ± 8.9 | — | — | 25.7 ± 0.9 | 0.72 | 80 |
Patient no. . | Hgb (g/L) . | MCV (fl) . | Retics (%) . | SI (μmol/L) . | TIBC (μmol/L) . | Tf sat (%) . | HbE (%) . | HbF (%) . | 51Cr RBC T½ (days) . | PITR3-150 . | RBC59Fe use (%) . |
---|---|---|---|---|---|---|---|---|---|---|---|
Mild cases | |||||||||||
1 | 80 | 66 | 4.2 | 21 | 45 | 46.2 | — | — | 10.5 | 2.5 | 49.0 |
2 | 103 | 69 | 1.2 | 15 | 29 | 51.0 | 50.44 | 37.68 | 19.5 | 2.8 | 30.0 |
3 | 85 | 62 | 1.1 | 33 | 35 | 93.7 | 75.80 | 13.67 | 20.7 | 2.0 | 43.0 |
4 | 94 | 68 | 2.0 | 30 | 32 | 93.6 | 61.75 | 22.76 | 13.5 | 3.7 | 37.2 |
5 | 72 | 69 | 1.4 | 15 | 26 | 56.5 | 45.45 | 27.06 | 16.8 | 4.5 | 27.8 |
6 | 123 | 73 | 0.8 | 20 | 32 | 67.4 | 33.94 | 34.50 | 21.0 | 3.3 | 27.0 |
Mean ± SD | 93 ± 18 | 67.8 ± 3.7 | 1.8 ± 1.2 | 22.3 ± 7.6 | 33.2 ± 6.6 | 68.1 ± 21.0 | 53.5 ± 16.0 | 27.1 ± 9.6 | 17.0 ± 4.3 | 3.1 ± 0.9 | 35.7 ± 9.0 |
Severe cases | |||||||||||
7 | 52 | 65 | 4.0 | 24 | 27 | 91.0 | 68.86 | 18.60 | 10.0 | 7.6 | — |
8 | 69 | 86 | 8.5 | 44 | 50 | 96.9 | 47.21 | 30.73 | 8.6 | 6.1 | 41.8 |
9 | 64 | 77 | 7.6 | 43 | 46 | 92.9 | 45.21 | 30.54 | 10.3 | 6.6 | 27.6 |
10 | 69 | 90 | 17.2 | 33 | 35 | 93.6 | 41.55 | 31.09 | 10.8 | 6.7 | 27.6 |
11 | 65 | 92 | 24.4 | 50 | 59 | 84.8 | 50.70 | 24.48 | 6.2 | 6.9 | 44.1 |
Mean ± SD | 64 ± 7 | 82.0 ± 11.1 | 12.3 ± 8.3 | 38.8 ± 10.3 | 43.4 ± 12.6 | 91.8 ± 4.5 | 50.7 ± 10.7 | 27.1 ± 5.5 | 9.2 ± 1.9 | 6.8 ± 0.5 | 35.3 ± 8.9 |
Pvalue | .01 | .04 | .05 | .02 | .15 | .04 | .76 | .99 | <.005 | <.0001 | .95 |
Normal | — | 84.9 ± 8.1 | 1.7 ± 1.6 | 20.6 ± 5.8 | 55.9 ± 7.2 | 35.8 ± 8.9 | — | — | 25.7 ± 0.9 | 0.72 | 80 |
Hb F indicates hemoglobin F.
Expressed as in Table 1.