Table 3.

Association between CCR5 and SDF1 genotypes and KS in HIV-infected men

GenotypeNo. (%) of men with KSNo. (%) of men without KSEvidence for association (P value)
LocusGenotype
SDF1 (G801A)     
 AA 2  (1.7) 5  (4.0)  .45 (F)  
 AG 39  (33.9) 31  (25.0) .23 (M) .13  
 GG 74  (64.3) 88  (71.0)  .27  
CCR5 (Δ32)     
 11 104  (90.4) 105  (84.0)   
 12 11  (9.6) 20  (16.0) .14 3-150 
 22   
GenotypeNo. (%) of men with KSNo. (%) of men without KSEvidence for association (P value)
LocusGenotype
SDF1 (G801A)     
 AA 2  (1.7) 5  (4.0)  .45 (F)  
 AG 39  (33.9) 31  (25.0) .23 (M) .13  
 GG 74  (64.3) 88  (71.0)  .27  
CCR5 (Δ32)     
 11 104  (90.4) 105  (84.0)   
 12 11  (9.6) 20  (16.0) .14 3-150 
 22   

A total of 115 men with KS and 126 without KS were studied. Genotypes for CCR5 and SDF1 were determined for a population of North American white men who acquired HIV infection through sex with other men. A χ2 test or the Mehta version of the Fisher exact test (M) was used to test the hypothesis at each locus (3 × 2 tables with 2 degrees of freedom) and for each of 3 possible genotypes (2 × 2 table). Not all samples were amplified at each locus.

F3-150

Because the 2/2 genotype was not observed, only a 2 × 2 test was performed.

F indicates Fisher exact test.

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