Table 1. Incidence of fusion transcripts... | American Society of Hematology

Table 1.

Incidence of fusion transcripts and IGH/TCR rearrangements as a function of age

Age (mean)	Genotypes					Rearrangements
Age (mean)	MLL-AF4 (%)	TEL-AML1 (%)	BCR-ABL (%)	E2A-PBX1 (%)	FT-negative (%)	IGH (%)	TCRG (%)	Vδ2-Dδ3 (%)
<2 y (1.1 yr)	2/10^* (20)	1/10 (10)	0/10 (0)	1/10 (10)	6/10^* (60)	10/11 (91)	1/11 (9)	6/7 (86)^†
2-14 y (5.9 y)	0/52 (0)	17/52 (33)	1/52 (2)	3/52 (6)	31/52 (60)	68/74 (92)	49/74 (66)	10/23 (43)
15-55 y (32.3 y)	10/66 (15)	nd^‡	17/66 (26)	8/66 (12)	31/66 (46)	57/66 (86)	40/66 (61)	6/33 (18)
>55 y (65.3 y)	2/12 (17)	nd	7/12 (58)	1/12 (8)	2/12 (17)	11/12 (92)	8/12 (66)	2/11 (18)
Total	14/140 (10)	18/62 (29)^1-153	25/140 (18)	13/140 (9)	70/140 (50)	145/163 (89)	98/163 (60)	24/74 (32)

Age (mean)	Genotypes					Rearrangements
Age (mean)	MLL-AF4 (%)	TEL-AML1 (%)	BCR-ABL (%)	E2A-PBX1 (%)	FT-negative (%)	IGH (%)	TCRG (%)	Vδ2-Dδ3 (%)
<2 y (1.1 yr)	2/10^* (20)	1/10 (10)	0/10 (0)	1/10 (10)	6/10^* (60)	10/11 (91)	1/11 (9)	6/7 (86)^†
2-14 y (5.9 y)	0/52 (0)	17/52 (33)	1/52 (2)	3/52 (6)	31/52 (60)	68/74 (92)	49/74 (66)	10/23 (43)
15-55 y (32.3 y)	10/66 (15)	nd^‡	17/66 (26)	8/66 (12)	31/66 (46)	57/66 (86)	40/66 (61)	6/33 (18)
>55 y (65.3 y)	2/12 (17)	nd	7/12 (58)	1/12 (8)	2/12 (17)	11/12 (92)	8/12 (66)	2/11 (18)
Total	14/140 (10)	18/62 (29)^1-153	25/140 (18)	13/140 (9)	70/140 (50)	145/163 (89)	98/163 (60)	24/74 (32)

FT indicates fusion transcript; nd, not determined.

The infant with an uncharacterized MLL rearrangement is not included.

Three-fourths in FT-negative infants.

Not systematically tested, but 0 of 23 were positive.

29% of children aged younger than 15 years.