Serum Ig concentrations
| Type of mouse . | Number of mice . | IgG (μg/ml) . | IgM (μg/ml) . | IgA (μg/ml) . |
|---|---|---|---|---|
| GFP | 5 | 1789 ± 312 | 709 ± 103 | 207 ± 26 |
| SDF-1 | 5 | 2745 ± 418* | 1197 ± 214* | 288 ± 45* |
| Intrakine | 5 | 980 ± 310* | 356 ± 123* | 144 ± 36* |
| Type of mouse . | Number of mice . | IgG (μg/ml) . | IgM (μg/ml) . | IgA (μg/ml) . |
|---|---|---|---|---|
| GFP | 5 | 1789 ± 312 | 709 ± 103 | 207 ± 26 |
| SDF-1 | 5 | 2745 ± 418* | 1197 ± 214* | 288 ± 45* |
| Intrakine | 5 | 980 ± 310* | 356 ± 123* | 144 ± 36* |
Serum Ig concentrations were reduced in intrakine-transduced mice but increased in SDF-1–transduced mice. Concentrations of different Ig isotypes were determined by ELISA. The mean ± SE for 3 independent experiments is shown. Statistical analysis was conducted (Student t test) to determine whether Ig concentrations from intrakine- or SDF-1–transduced mice were significantly different from EGFP-1–transduced mice.
P < .01.