Table 5. 5q status in purified myeloid... | American Society of Hematology

Table 5.

5q status in purified myeloid and B lymphoid progenitor subpopulations in bone marrow

Patient	CD34⁺CD33⁺		CD34⁺CD19⁺
Patient	% of CD34⁺	% 5q−	% of CD34⁺	% 5q−
2	nd	nd	2.0	67 (54)^5-150
3	85	94	0^5-151	na
4	58	99	6.0	90^5-152
5	nd	nd	0.2	6
6	83	>99	0^5-151	na
8	46 (63)^5-150	76	2.6	0 (36)^5-150
9	nd	nd	4.0	25
11	27	99	0^5-151	na
12	18	98	0^5-151	na
Mean (SEM)	53 (11.5)	94 (3.8)	3.1 (1.1)	37 (17.0)

Patient	CD34⁺CD33⁺		CD34⁺CD19⁺
Patient	% of CD34⁺	% 5q−	% of CD34⁺	% 5q−
2	nd	nd	2.0	67 (54)^5-150
3	85	94	0^5-151	na
4	58	99	6.0	90^5-152
5	nd	nd	0.2	6
6	83	>99	0^5-151	na
8	46 (63)^5-150	76	2.6	0 (36)^5-150
9	nd	nd	4.0	25
11	27	99	0^5-151	na
12	18	98	0^5-151	na
Mean (SEM)	53 (11.5)	94 (3.8)	3.1 (1.1)	37 (17.0)

The frequency and 5q status of purified myeloid (CD34⁺CD33⁺) and pro-B (CD34⁺CD19⁺) progenitor cell subpopulations were investigated in 5q− deleted MDS patients. Corresponding normal BM populations were isolated from 2 individuals. The mean percentages of 1O + 2G cells were 5.0% and 2.9% for normal CD34⁺CD33⁺ and CD34⁺CD19⁺ cells, respectively.

nd indicates not determined; na, not applicable.

F5-150

Fewer than 100 cells counted (counted cells are shown in parentheses).

F5-151

Subpopulation too small for sorting.

F5-152

Mean of 2 separate experiments performed with an interval of 12 months.

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