Table 3. Frequency of 5q deletions in... | American Society of Hematology

Table 3.

Frequency of 5q deletions in CD34⁺, CD34⁺CD38⁺, and CD34⁺CD38⁻ cells

Patient	% cells with 5q deletions
Patient	CD34⁺ cells	CD34⁺CD38⁺cells	CD34⁺CD38⁻ cells
1	nd	98	98
3	nd	97	98
4	97	98	94
5	94	nd	nd
6	nd	99	> 99
7	96^3-150	88	> 99
8	89^3-150	95	> 99
10	98	98	99
11	nd	93	99
12	95	98	99
Mean (SEM)	95 (1.3)	96 (1.2)	98 (1.0)

Patient	% cells with 5q deletions
Patient	CD34⁺ cells	CD34⁺CD38⁺cells	CD34⁺CD38⁻ cells
1	nd	98	98
3	nd	97	98
4	97	98	94
5	94	nd	nd
6	nd	99	> 99
7	96^3-150	88	> 99
8	89^3-150	95	> 99
10	98	98	99
11	nd	93	99
12	95	98	99
Mean (SEM)	95 (1.3)	96 (1.2)	98 (1.0)

CD34⁺CD38⁺ and CD34⁺CD38⁻ cells were purified as described in “Materials and methods” and subsequently transferred to slides by cytospin centrifugation before being analyzed by FISH. Normal BM CD34⁺, CD34⁺CD38⁺, and CD34⁺CD38⁻ cells from 2 individuals were sorted and analyzed by FISH in an identical manner, and the mean percentage of 1O + 2G cells was 3.2%.

nd indicates not determined.

F3-150

Fewer than 100 cells counted.

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