Detection of t(11;18)(q21;q21) using interphase FISH with PACs 166G16 and 59N7 in 122 cases of B-cell NHL.
Diagnosis . | FISH analysis . | Cytogenetic analysis . | ||
---|---|---|---|---|
Cases analyzed, no. . | t(11;18)+ cases, no. . | Cases analyzed/abnormal, no. . | t(11;18)− cases, no. . | |
Extranodal MZBCL of MALT-type | 41 | 8 | 16/6 | 2 |
Stomach | 24 | 6 | 10/3 | 1 |
Ileum | 3 | 2* | 1/1 | 1 |
Colon | 1 | 0 | 1/0 | 0 |
Parotid | 4 | 0 | 0 | 0 |
Orbit | 5 | 0 | 2/0 | 0 |
Cutis | 2 | 0 | 0 | 0 |
Liver | 1 | 0 | 1/1 | 0 |
Breast | 1 | 0 | 1/1 | 0 |
MZBCL | ||||
Nodal | 19 | 0 | 18/18 | 0 |
Splenic | 22 | 0 | 12/11 | 0 |
DLCL | ||||
Gastric | 10 | 0 | 1/0 | 0 |
Nodal | 10 | 0 | 10/10 | 0 |
Hairy cell leukemia | 10 | 0 | 0 | 0 |
Follicle center cell lymphoma | 10 | 0 | 10/10 | 0 |
Diagnosis . | FISH analysis . | Cytogenetic analysis . | ||
---|---|---|---|---|
Cases analyzed, no. . | t(11;18)+ cases, no. . | Cases analyzed/abnormal, no. . | t(11;18)− cases, no. . | |
Extranodal MZBCL of MALT-type | 41 | 8 | 16/6 | 2 |
Stomach | 24 | 6 | 10/3 | 1 |
Ileum | 3 | 2* | 1/1 | 1 |
Colon | 1 | 0 | 1/0 | 0 |
Parotid | 4 | 0 | 0 | 0 |
Orbit | 5 | 0 | 2/0 | 0 |
Cutis | 2 | 0 | 0 | 0 |
Liver | 1 | 0 | 1/1 | 0 |
Breast | 1 | 0 | 1/1 | 0 |
MZBCL | ||||
Nodal | 19 | 0 | 18/18 | 0 |
Splenic | 22 | 0 | 12/11 | 0 |
DLCL | ||||
Gastric | 10 | 0 | 1/0 | 0 |
Nodal | 10 | 0 | 10/10 | 0 |
Hairy cell leukemia | 10 | 0 | 0 | 0 |
Follicle center cell lymphoma | 10 | 0 | 10/10 | 0 |
Indicates that in one of the two cases, an ileum biopsy was analyzed; however, in addition to the ileum, other segments of the gastrointestinal tract were involved by the MALT lymphoma (Table 2, case 6).