Recurring chromosome abnormalities in this series
| Cases, no. . | Abnormal karotype, % (n = 201) . | Abnormalities . | Loci affected . |
|---|---|---|---|
| 38 | 18.9 | del(6q) | D6S24652; D6S28353 |
| 22 | 10.9 | +8* | U |
| 14 | 7.0 | t(11;14)(p13;q11) | LMO2/RBTN2/TTG2, TCRA/D9 |
| 12 | 6.0 | t(10;14)(q24;q11), del(9p) | TCL3/HOX11, TCRA/D9; p16/CDKN2A, P15/CDKN2B9 |
| 11 | 5.5 | del(5q) | U |
| 10 | 5.0 | +21 (8/10 have Down's syndrome) | U |
| 9 | 4.5 | del(11q), del(12p) | U; ?TEL/ETV654 |
| 8 | 4.0 | +19† | U |
| 7 | 3.5 | del(9q), i(9q) | ?GAS155; U |
| 6 | 3.0 | +7, del(7q), del(13q) | U; U; ?RB19 |
| 5 | 2.5 | t(1;14)(p34;q11), −9 | SCL/TCL5/TAL1, TCRD9; ?p16/CDKN2A, ?p15/CDKN2B9 |
| 4 | 2.0 | +4, +9, t(10;11)(p13-15;q13-21), +17 | U; U; AF10, CALM56; U |
| 3 | 1.5 | dup(2)(q21-32q31-37), inv(7)(p15q34-36), t(8;14)(q24;q11), t(9;22)(q34;q11), t(11;19)(q23;p13), +20, −Y | U; TCRG, TCRB57; CMYC, TCRA9; ABL, BCR58; MLL, ENL54; U; U |
| 2 | 1.0 | del(1)(p22), del(5)(p13), +6, i(7q), t(7;10)(q34-35;q24), del(7)(p13-15), t(8;12)(q13;p13), +10, +11, der(12)t(7;12)(q11;p11), inv(12)(p12q15-21), t(12;13)(p11-12;q12), +14, i(17q), +18, +22 | U; U; U; U; TCRB, TCL3/HOX1154; U; U, ?TEL/ETV6; U; U; U; U, ?HMGIC59; ?TEL/ETV6; CDX260; U; ?P539; U; U |
| Cases, no. . | Abnormal karotype, % (n = 201) . | Abnormalities . | Loci affected . |
|---|---|---|---|
| 38 | 18.9 | del(6q) | D6S24652; D6S28353 |
| 22 | 10.9 | +8* | U |
| 14 | 7.0 | t(11;14)(p13;q11) | LMO2/RBTN2/TTG2, TCRA/D9 |
| 12 | 6.0 | t(10;14)(q24;q11), del(9p) | TCL3/HOX11, TCRA/D9; p16/CDKN2A, P15/CDKN2B9 |
| 11 | 5.5 | del(5q) | U |
| 10 | 5.0 | +21 (8/10 have Down's syndrome) | U |
| 9 | 4.5 | del(11q), del(12p) | U; ?TEL/ETV654 |
| 8 | 4.0 | +19† | U |
| 7 | 3.5 | del(9q), i(9q) | ?GAS155; U |
| 6 | 3.0 | +7, del(7q), del(13q) | U; U; ?RB19 |
| 5 | 2.5 | t(1;14)(p34;q11), −9 | SCL/TCL5/TAL1, TCRD9; ?p16/CDKN2A, ?p15/CDKN2B9 |
| 4 | 2.0 | +4, +9, t(10;11)(p13-15;q13-21), +17 | U; U; AF10, CALM56; U |
| 3 | 1.5 | dup(2)(q21-32q31-37), inv(7)(p15q34-36), t(8;14)(q24;q11), t(9;22)(q34;q11), t(11;19)(q23;p13), +20, −Y | U; TCRG, TCRB57; CMYC, TCRA9; ABL, BCR58; MLL, ENL54; U; U |
| 2 | 1.0 | del(1)(p22), del(5)(p13), +6, i(7q), t(7;10)(q34-35;q24), del(7)(p13-15), t(8;12)(q13;p13), +10, +11, der(12)t(7;12)(q11;p11), inv(12)(p12q15-21), t(12;13)(p11-12;q12), +14, i(17q), +18, +22 | U; U; U; U; TCRB, TCL3/HOX1154; U; U, ?TEL/ETV6; U; U; U; U, ?HMGIC59; ?TEL/ETV6; CDX260; U; ?P539; U; U |