Primary causes of death
| . | Tacrolimus (N = 90) N (%) . | CSP (N = 90) N (%) . |
|---|---|---|
| GVHD | 3 (3) | 12 (13) |
| Graft failure | 3 (3) | 6 (6) |
| Regimen-related toxicity | 9 (10) | 8 (9) |
| Interstitial pneumonia | 1 (1) | 0 |
| Relapse | 11 (12) | 7 (8) |
| Infection8-150 | 12 (13) | 8 (9) |
| Viral | 2 (2) | 1 (1) |
| Bacterial | 3 (3) | 3 (3) |
| Fungal | 6 (6) | 4 (4) |
| Pneumocystis carinii | 1 (1) | |
| Other | 2 (2) | 4 (4) |
| Total | 41 (46) | 45 (50) |
| . | Tacrolimus (N = 90) N (%) . | CSP (N = 90) N (%) . |
|---|---|---|
| GVHD | 3 (3) | 12 (13) |
| Graft failure | 3 (3) | 6 (6) |
| Regimen-related toxicity | 9 (10) | 8 (9) |
| Interstitial pneumonia | 1 (1) | 0 |
| Relapse | 11 (12) | 7 (8) |
| Infection8-150 | 12 (13) | 8 (9) |
| Viral | 2 (2) | 1 (1) |
| Bacterial | 3 (3) | 3 (3) |
| Fungal | 6 (6) | 4 (4) |
| Pneumocystis carinii | 1 (1) | |
| Other | 2 (2) | 4 (4) |
| Total | 41 (46) | 45 (50) |
Two patients with fungus infection in the tacrolimus group also had concomitant viral infections; 2 patients with fungus infection in the CSP group also had concomitant bacterial infections.