Table 8.

Primary causes of death

Tacrolimus
(N = 90)
N (%)
CSP
(N = 90)
N (%)
GVHD 3  (3) 12  (13) 
Graft failure 3  (3) 6  (6)  
Regimen-related toxicity 9  (10) 8  (9)  
Interstitial pneumonia 1  (1) 0  
Relapse 11  (12) 7  (8) 
Infection8-150 12  (13) 8  (9)  
 Viral 2  (2) 1  (1)  
 Bacterial 3  (3) 3  (3)  
 Fungal 6  (6) 4  (4)  
Pneumocystis carinii 1  (1)  
 Other 2  (2) 4  (4)  
 Total 41  (46) 45  (50) 
Tacrolimus
(N = 90)
N (%)
CSP
(N = 90)
N (%)
GVHD 3  (3) 12  (13) 
Graft failure 3  (3) 6  (6)  
Regimen-related toxicity 9  (10) 8  (9)  
Interstitial pneumonia 1  (1) 0  
Relapse 11  (12) 7  (8) 
Infection8-150 12  (13) 8  (9)  
 Viral 2  (2) 1  (1)  
 Bacterial 3  (3) 3  (3)  
 Fungal 6  (6) 4  (4)  
Pneumocystis carinii 1  (1)  
 Other 2  (2) 4  (4)  
 Total 41  (46) 45  (50) 
F8-150

Two patients with fungus infection in the tacrolimus group also had concomitant viral infections; 2 patients with fungus infection in the CSP group also had concomitant bacterial infections.

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