Distribution of grade 2-4 acute GVHD based on type of HLA match
| . | Tacrolimus (%) N = 90 . | CSP (%) N = 90 . |
|---|---|---|
| HLA complete match acute GVHD | 37/75 (49) | 51/74 (70) |
| HLA class I mismatch acute GVHD | 7/11 (64) | 4/5 (80) |
| HLA class II mismatch acute GVHD | 2/4 (50) | 8/11 (73) |
| . | Tacrolimus (%) N = 90 . | CSP (%) N = 90 . |
|---|---|---|
| HLA complete match acute GVHD | 37/75 (49) | 51/74 (70) |
| HLA class I mismatch acute GVHD | 7/11 (64) | 4/5 (80) |
| HLA class II mismatch acute GVHD | 2/4 (50) | 8/11 (73) |
A stratified analysis of acute GVHD and the effect of HLA match demonstrated that the decreased incidence of acute GVHD in the tacrolimus group is highly significant (P = .0066).