Decreased transcripts in MADCs
| Fold . | n . | SAGE tag . | UniGene cluster . | Description . | ||||
|---|---|---|---|---|---|---|---|---|
| IMDC . | MADC . | Mo . | M-CSF . | GM-CSF . | ||||
| 68 | 68 | 0 | 1 | 24 | 44 | AGAAGTGTCC | 85226 | Lipase A, lysosomal acid, cholesterol esterase |
| 39 | 38 | 0 | 4 | 10 | 6 | CACCACGGTG | 107325 | α-1-antichymotrypsin |
| 33 | 33 | 1 | 4 | 4 | 3 | AGCTGTCCCC | No match | |
| 28 | 58 | 2 | 38 | 71 | 196 | GGGGCAACAG | 214742 | CDW52 antigen (CAMPATH-1 antigen) |
| 23 | 23 | 0 | 7 | 7 | 5 | AGAAGCCGTG | 172831 | CD11b (p170) |
| 23 | 23 | 1 | 15 | 15 | 31 | CTGGCGCGAG | 83656 | Rho GDF dissociation inhibitor (GDI) β |
| 22 | 22 | 0 | 66 | 19 | 25 | ATGTGTAACG | 61256 | S100 calcium-binding protein A4 |
| 20 | 20 | 1 | 1 | 1 | 2 | TTTGCTCTCC | 75350 | Vinculin |
| 19 | 19 | 0 | 0 | 0 | 0 | CCTCTGGGCA | 167256 | P460 (cytochrome) oxidoreductase |
| 18 | 18 | 0 | 0 | 0 | 2 | CCAAGACTTC | No match | |
| 18 | 35 | 2 | 58 | 107 | 167 | GCGGTTGTGG | 79358 | Lysosomal-associated multiapanning membrane protein-5 |
| 17 | 52 | 3 | 1 | 1 | 1 | AGCCACCGCA | 242 | Glucose-6-phosphatase, catalytic |
| 17 | 17 | 0 | 3 | 24 | 3 | CCGACGGGCG | No match | |
| 17 | 17 | 1 | 8 | 6 | 5 | TGGCTGGCCA | 174142 | Colony-stimulating factor-1 receptor |
| 16 | 16 | 0 | 1 | 0 | 0 | TTGAGACCTC | 80424 | Coagulation factor XIII, A1 polypeptide |
| 15 | 15 | 0 | 2 | 1 | 3 | ACTGACTGCA | 23262 | Ribonuclease, RNase A family, k6 |
| 15 | 15 | 0 | 11 | 6 | 3 | CGTGTGCCTG | 108713 | ESTs |
| 15 | 15 | 1 | 3 | 15 | 12 | TGGCCATCTG | 184052 | ESTs |
| 14 | 14 | 0 | 0 | 8 | 17 | TCTTGATTTA | 74561 | α2-macroglobulin |
| 14 | 14 | 1 | 0 | 32 | 36 | TGTCCCAGCC | 1211 | Acid phosphatase-β, tartrate resistant |
| 14 | 14 | 1 | 6 | 11 | 7 | CTGCTAACCC | 170310 | ESTs |
| 14 | 14 | 1 | 14 | 14 | 23 | CCAGGCAGGG | 117339 | cDNA DKFZp586C1522 |
| 13 | 13 | 0 | 2 | 4 | 6 | GGGGGTGAAG | 76171 | CCAAT/enhancer-binding protein (C/EBP), α |
| 13 | 13 | 0 | 4 | 1 | 0 | AGTCTCTCTT | No match | |
| 13 | 25 | 2 | 12 | 13 | 8 | CCACACAAGC | 102737 | ESTs |
| 12 | 12 | 1 | 0 | 0 | 3 | ATGGAAGTCT | 155939 | Inosilol polyphosphate-5-phosphatase, 145 kd |
| 12 | 12 | 1 | 4 | 1 | 0 | AAAAGAAACT | 172182 | Poly(A)-binding protein-like 1 |
| 12 | 12 | 1 | 26 | 14 | 7 | TCACAAGCAA | 146763 | Nascent polypeptide-associated complex α polypeptide |
| 11 | 11 | 0 | 12 | 5 | 13 | CTGGCCCGAG | 83656 | Rho GDP dissociation inhibitor (GDI) β |
| 11 | 11 | 1 | 0 | 1 | 0 | GATACAGCCA | 1416 | CD33 |
| 11 | 11 | 1 | 0 | 0 | 1 | TGTGAACAAC | 129771 | ESTs |
| 11 | 11 | 1 | 3 | 1 | 0 | ACCCCCGGGC | Multiple match | |
| 11 | 11 | 1 | 4 | 10 | 13 | GTCTGAGCTC | 66915 | ESTs |
| 10 | 52 | 5 | 3 | 713 | 849 | TGGCCCCAGG | 132776 | Apolipoprotein C-1 |
| 10 | 10 | 0 | 0 | 0 | 8 | GCCTACCCGA | 23582 | GA733-1 |
| 10 | 10 | 0 | 0 | 3 | 11 | ACCCAGGGTA | 44234 | ESTs |
| 10 | 10 | 0 | 0 | 1 | 2 | CCCTCGGTCC | No match | |
| 10 | 10 | 0 | 2 | 14 | 8 | TCTCTGATGC | 8441 | cDNA DKF2pS86J021 |
| 10 | 10 | 0 | 2 | 9 | 3 | GCCACTACCC | 71475 | ESTs |
| 10 | 10 | 0 | 2 | 28 | 65 | ACTATTTCCA | 574 | Fructose-bisphosphatase 1 |
| 10 | 10 | 0 | 3 | 2 | 4 | AGGACACCGC | 77783 | c-src tyrosine kinase |
| 10 | 10 | 1 | 0 | 0 | 3 | CTGATCTCCA | Multiple match | |
| 10 | 10 | 1 | 9 | 6 | 0 | TGATGTTTGA | 75416 | KIAA0058 gene product |
| 9 | 28 | 3 | 47 | 17 | 11 | TCTGTACACC | 182740 | Aldolase β, fructose-bisphosphate |
| 9 | 27 | 3 | 2 | 15 | 4 | TGGCGTACGG | 159546 | ATP-binding cassette, subfamily D (ALD), member 1 |
| 9 | 9 | 0 | 0 | 23 | 18 | AAGATTGGTG | 1244 | CDS antigen (p24) |
| 9 | 9 | 0 | 0 | 0 | 0 | TGCAGAAGAA | 75182 | Mannose receptor, C type 1 |
| 9 | 9 | 0 | 0 | 1 | 0 | CCTCACTACC | 99307 | ESTs |
| 9 | 8 | 0 | 0 | 2 | 1 | GGTGTGCTTG | 155182 | Homo sapiens mRNA for KIAA1036 protein, complete cds |
| 9 | 9 | 0 | 0 | 0 | 2 | GGTCCCCTAC | 151761 | KIAA0100 gene product |
| Fold . | n . | SAGE tag . | UniGene cluster . | Description . | ||||
|---|---|---|---|---|---|---|---|---|
| IMDC . | MADC . | Mo . | M-CSF . | GM-CSF . | ||||
| 68 | 68 | 0 | 1 | 24 | 44 | AGAAGTGTCC | 85226 | Lipase A, lysosomal acid, cholesterol esterase |
| 39 | 38 | 0 | 4 | 10 | 6 | CACCACGGTG | 107325 | α-1-antichymotrypsin |
| 33 | 33 | 1 | 4 | 4 | 3 | AGCTGTCCCC | No match | |
| 28 | 58 | 2 | 38 | 71 | 196 | GGGGCAACAG | 214742 | CDW52 antigen (CAMPATH-1 antigen) |
| 23 | 23 | 0 | 7 | 7 | 5 | AGAAGCCGTG | 172831 | CD11b (p170) |
| 23 | 23 | 1 | 15 | 15 | 31 | CTGGCGCGAG | 83656 | Rho GDF dissociation inhibitor (GDI) β |
| 22 | 22 | 0 | 66 | 19 | 25 | ATGTGTAACG | 61256 | S100 calcium-binding protein A4 |
| 20 | 20 | 1 | 1 | 1 | 2 | TTTGCTCTCC | 75350 | Vinculin |
| 19 | 19 | 0 | 0 | 0 | 0 | CCTCTGGGCA | 167256 | P460 (cytochrome) oxidoreductase |
| 18 | 18 | 0 | 0 | 0 | 2 | CCAAGACTTC | No match | |
| 18 | 35 | 2 | 58 | 107 | 167 | GCGGTTGTGG | 79358 | Lysosomal-associated multiapanning membrane protein-5 |
| 17 | 52 | 3 | 1 | 1 | 1 | AGCCACCGCA | 242 | Glucose-6-phosphatase, catalytic |
| 17 | 17 | 0 | 3 | 24 | 3 | CCGACGGGCG | No match | |
| 17 | 17 | 1 | 8 | 6 | 5 | TGGCTGGCCA | 174142 | Colony-stimulating factor-1 receptor |
| 16 | 16 | 0 | 1 | 0 | 0 | TTGAGACCTC | 80424 | Coagulation factor XIII, A1 polypeptide |
| 15 | 15 | 0 | 2 | 1 | 3 | ACTGACTGCA | 23262 | Ribonuclease, RNase A family, k6 |
| 15 | 15 | 0 | 11 | 6 | 3 | CGTGTGCCTG | 108713 | ESTs |
| 15 | 15 | 1 | 3 | 15 | 12 | TGGCCATCTG | 184052 | ESTs |
| 14 | 14 | 0 | 0 | 8 | 17 | TCTTGATTTA | 74561 | α2-macroglobulin |
| 14 | 14 | 1 | 0 | 32 | 36 | TGTCCCAGCC | 1211 | Acid phosphatase-β, tartrate resistant |
| 14 | 14 | 1 | 6 | 11 | 7 | CTGCTAACCC | 170310 | ESTs |
| 14 | 14 | 1 | 14 | 14 | 23 | CCAGGCAGGG | 117339 | cDNA DKFZp586C1522 |
| 13 | 13 | 0 | 2 | 4 | 6 | GGGGGTGAAG | 76171 | CCAAT/enhancer-binding protein (C/EBP), α |
| 13 | 13 | 0 | 4 | 1 | 0 | AGTCTCTCTT | No match | |
| 13 | 25 | 2 | 12 | 13 | 8 | CCACACAAGC | 102737 | ESTs |
| 12 | 12 | 1 | 0 | 0 | 3 | ATGGAAGTCT | 155939 | Inosilol polyphosphate-5-phosphatase, 145 kd |
| 12 | 12 | 1 | 4 | 1 | 0 | AAAAGAAACT | 172182 | Poly(A)-binding protein-like 1 |
| 12 | 12 | 1 | 26 | 14 | 7 | TCACAAGCAA | 146763 | Nascent polypeptide-associated complex α polypeptide |
| 11 | 11 | 0 | 12 | 5 | 13 | CTGGCCCGAG | 83656 | Rho GDP dissociation inhibitor (GDI) β |
| 11 | 11 | 1 | 0 | 1 | 0 | GATACAGCCA | 1416 | CD33 |
| 11 | 11 | 1 | 0 | 0 | 1 | TGTGAACAAC | 129771 | ESTs |
| 11 | 11 | 1 | 3 | 1 | 0 | ACCCCCGGGC | Multiple match | |
| 11 | 11 | 1 | 4 | 10 | 13 | GTCTGAGCTC | 66915 | ESTs |
| 10 | 52 | 5 | 3 | 713 | 849 | TGGCCCCAGG | 132776 | Apolipoprotein C-1 |
| 10 | 10 | 0 | 0 | 0 | 8 | GCCTACCCGA | 23582 | GA733-1 |
| 10 | 10 | 0 | 0 | 3 | 11 | ACCCAGGGTA | 44234 | ESTs |
| 10 | 10 | 0 | 0 | 1 | 2 | CCCTCGGTCC | No match | |
| 10 | 10 | 0 | 2 | 14 | 8 | TCTCTGATGC | 8441 | cDNA DKF2pS86J021 |
| 10 | 10 | 0 | 2 | 9 | 3 | GCCACTACCC | 71475 | ESTs |
| 10 | 10 | 0 | 2 | 28 | 65 | ACTATTTCCA | 574 | Fructose-bisphosphatase 1 |
| 10 | 10 | 0 | 3 | 2 | 4 | AGGACACCGC | 77783 | c-src tyrosine kinase |
| 10 | 10 | 1 | 0 | 0 | 3 | CTGATCTCCA | Multiple match | |
| 10 | 10 | 1 | 9 | 6 | 0 | TGATGTTTGA | 75416 | KIAA0058 gene product |
| 9 | 28 | 3 | 47 | 17 | 11 | TCTGTACACC | 182740 | Aldolase β, fructose-bisphosphate |
| 9 | 27 | 3 | 2 | 15 | 4 | TGGCGTACGG | 159546 | ATP-binding cassette, subfamily D (ALD), member 1 |
| 9 | 9 | 0 | 0 | 23 | 18 | AAGATTGGTG | 1244 | CDS antigen (p24) |
| 9 | 9 | 0 | 0 | 0 | 0 | TGCAGAAGAA | 75182 | Mannose receptor, C type 1 |
| 9 | 9 | 0 | 0 | 1 | 0 | CCTCACTACC | 99307 | ESTs |
| 9 | 8 | 0 | 0 | 2 | 1 | GGTGTGCTTG | 155182 | Homo sapiens mRNA for KIAA1036 protein, complete cds |
| 9 | 9 | 0 | 0 | 0 | 2 | GGTCCCCTAC | 151761 | KIAA0100 gene product |
The 50 transcripts displaying the largest decrease in expression are listed. MADCs are listed by fold reduction. n indicates the number of times the tag was identified. Conditions are described in Figure 2. More information is available on the Internet athttp://www.prevent.m.u-tokyo.ac/jp/SAGE.html/. In this table, each number of tags from IMDC (58 540), MADC (31 837), Mo (57 560, monocytes), M-CSF (55 856, M-CSF–induced macrophages), and GM-CSF (57 463, GM-CSF–induced macrophages) was normalized to 31 837.