Increased transcripts in MADCs
| Fold . | n . | SAGE tag . | UniGene cluster . | Description . | |||||
|---|---|---|---|---|---|---|---|---|---|
| IMDC . | MADC . | LPS-Mo . | Mo . | M-CSF . | GM-CSF . | ||||
| 70 | 3 | 210 | 2 | 2 | 1 | 18 | CAAATCCAAA | 227400 | Germinal center kinase–related protein kinase |
| 67 | 1 | 67 | 6 | 0 | 0 | 0 | TTCTGCTTTC | 1652 | CCR7 |
| 66 | 1 | 86 | 0 | 0 | 0 | 0 | GTAGCGCCTC | 143212 | Cystatin F (leukocystatin) |
| 47 | 1 | 47 | 4 | 0 | 6 | 11 | GATCCCAACT | 118766 | Metallothionein 2A |
| 43 | 0 | 43 | 1 | 0 | 0 | 0 | GGCGTTTAGA | No match | |
| 42 | 0 | 42 | 11 | 0 | 0 | 0 | AAAAATCGGC | 226695 | RANTES |
| 41 | 2 | 62 | 48 | 4 | 0 | 1 | AATCTGCGCC | 833 | Interferon-stimulated protein, 15 kd |
| 40 | 0 | 40 | 0 | 0 | 0 | 0 | CCAGGGGAGA | 2867 | Interferon-α–inducible protein p27 |
| 38 | 1 | 39 | 3 | 1 | 1 | 0 | GGTGCCCAGT | 75607 | MARCKS, 8CK-L |
| 37 | 4 | 148 | 0 | 0 | 1 | 1 | ATAGTAGCTT | 118400 | Actin-bundling protein |
| 36 | 1 | 36 | 0 | 1 | 0 | 0 | CGGAGCCGGC | 34267 | ESTs |
| 31 | 0 | 31 | 0 | 0 | 0 | 0 | GCTCCCTACG | 185705 | EBI3 |
| 30 | 1 | 30 | 11 | 1 | 1 | 0 | AGTGCCGTGT | 76391 | Interferon-inducible protein p75 |
| 27 | 0 | 27 | 0 | 0 | 0 | 0 | CATCTCACTC | No match | |
| 27 | 0 | 27 | 0 | 0 | 0 | 0 | GCCCTGCTAC | 50002 | ELC |
| 26 | 0 | 26 | 54 | 4 | 1 | 1 | GCTTGCAAAA | 177781 | Superoxide dismutase 2 |
| 26 | 1 | 26 | 1 | 0 | 1 | 0 | CCTCCCTGCT | 90790 | ESTs |
| 25 | 1 | 25 | 0 | 0 | 0 | 0 | TGTTTCCTTA | 10887 | DC-LAMP |
| 25 | 1 | 25 | 20 | 4 | 2 | 0 | GGGTTTGTTT | 75889 | Proline-rich protein with nuclear targeting signal |
| 25 | 1 | 25 | 13 | 49 | 6 | 3 | TCACAGCTGT | 77054 | B-cell translocation gene 1, antiproliferative |
| 24 | 0 | 24 | 0 | 0 | 0 | 24 | TAAATCCAAA | 224982 | ESTs |
| 23 | 2 | 46 | 1 | 0 | 0 | 0 | GATCAATCAG | 16530 | PARC |
| 22 | 1 | 22 | 0 | 0 | 0 | 0 | GTGCCTTTTT | 204290 | cDNA DKFZp588N2119 |
| 21 | 0 | 21 | 0 | 0 | 0 | 0 | GCGGCTCCTG | No match | |
| 21 | 0 | 21 | 3 | 1 | 0 | 0 | AACCCCTGGA | 255647 | ESTs |
| 21 | 0 | 21 | 7 | 0 | 0 | 0 | AGCGGCTACA | 183487 | HEM46 (interferon-stimulated gene 20 kd) |
| 21 | 1 | 21 | 0 | 0 | 0 | 0 | GGCAGCCAGA | 75061 | MacMARCKS |
| 21 | 1 | 21 | 0 | 0 | 0 | 5 | AGCAAATCCA | No match | |
| 20 | 0 | 20 | 2 | 0 | 0 | 0 | CTTGCAAACC | 229838 | ESTs |
| 20 | 1 | 20 | 8 | 11 | 2 | 6 | ATCCCTCAGT | 181243 | Activating transcription factor 4 |
| 18 | 18 | 338 | 12 | 0 | 4 | 65 | AACGGGGCCC | 97203 | MDC |
| 17 | 0 | 17 | 11 | 2 | 1 | 0 | GTCTTAAAGT | 177781 | Superoxide dismutase 2, mitochondrial |
| 16 | 0 | 16 | 7 | 4 | 0 | 0 | TCCGCAAGGT | 37617 | ESTs |
| 16 | 1 | 16 | 0 | 0 | 0 | 0 | GCAGGCCAAG | Multiple match | |
| 15 | 7 | 108 | 24 | 14 | 70 | 30 | CGCCGACGAT | 21205 | Interferon-α–inducible protein (clone IFI-6-16) |
| 14 | 0 | 14 | 0 | 0 | 0 | 0 | TCTGTTGGAC | 218318 | ESTs |
| 14 | 0 | 14 | 6 | 0 | 0 | 0 | CAGGTGAAAC | Multiple match | |
| 14 | 1 | 14 | 4 | 6 | 1 | 3 | CCCCTGGCTG | 920 | Modulator recognition factor I |
| 14 | 8 | 110 | 21 | 6 | 11 | 7 | TCCGTGGTTG | 79518 | Neuronal tissue–enriched acidic protein |
| 13 | 0 | 13 | 0 | 8 | 0 | 0 | TTTGGGACCC | 270 | Sec7 and coiled/cell domains, binding protein |
| 12 | 68 | 831 | 15 | 0 | 0 | 1 | GGCACAAAGG | 86742 | TARC |
| 12 | 0 | 12 | 0 | 1 | 0 | 0 | CAGCCTGCGA | 35140 | Serine/threonine kinase 4 |
| 12 | 0 | 12 | 0 | 0 | 0 | 4 | GCAAATCCAA | No match | |
| 12 | 0 | 12 | 2 | 1 | 0 | 0 | ACCATTGGAT | 146360 | Interferon-induced protein 17 |
| 12 | 0 | 12 | 5 | 0 | 1 | 0 | GACAGATGGA | 83575 | ESTs |
| 12 | 1 | 12 | 0 | 0 | 0 | 0 | TTTCATCGTA | 106149 | ESTs |
| 12 | 1 | 12 | 0 | 1 | 0 | 0 | TGTGGAAACC | 80205 | plm-2 oncogene |
| 12 | 1 | 12 | 1 | 0 | 3 | 5 | ATGGTCTACG | 98593 | ESTs |
| 12 | 1 | 12 | 1 | 10 | 0 | 2 | GTGCCCGTGC | 83846 | Trisephosphate isomerase 1 |
| 12 | 5 | 59 | 59 | 1 | 15 | 11 | ACTGTGGCGG | 112242 | ESTs |
| Fold . | n . | SAGE tag . | UniGene cluster . | Description . | |||||
|---|---|---|---|---|---|---|---|---|---|
| IMDC . | MADC . | LPS-Mo . | Mo . | M-CSF . | GM-CSF . | ||||
| 70 | 3 | 210 | 2 | 2 | 1 | 18 | CAAATCCAAA | 227400 | Germinal center kinase–related protein kinase |
| 67 | 1 | 67 | 6 | 0 | 0 | 0 | TTCTGCTTTC | 1652 | CCR7 |
| 66 | 1 | 86 | 0 | 0 | 0 | 0 | GTAGCGCCTC | 143212 | Cystatin F (leukocystatin) |
| 47 | 1 | 47 | 4 | 0 | 6 | 11 | GATCCCAACT | 118766 | Metallothionein 2A |
| 43 | 0 | 43 | 1 | 0 | 0 | 0 | GGCGTTTAGA | No match | |
| 42 | 0 | 42 | 11 | 0 | 0 | 0 | AAAAATCGGC | 226695 | RANTES |
| 41 | 2 | 62 | 48 | 4 | 0 | 1 | AATCTGCGCC | 833 | Interferon-stimulated protein, 15 kd |
| 40 | 0 | 40 | 0 | 0 | 0 | 0 | CCAGGGGAGA | 2867 | Interferon-α–inducible protein p27 |
| 38 | 1 | 39 | 3 | 1 | 1 | 0 | GGTGCCCAGT | 75607 | MARCKS, 8CK-L |
| 37 | 4 | 148 | 0 | 0 | 1 | 1 | ATAGTAGCTT | 118400 | Actin-bundling protein |
| 36 | 1 | 36 | 0 | 1 | 0 | 0 | CGGAGCCGGC | 34267 | ESTs |
| 31 | 0 | 31 | 0 | 0 | 0 | 0 | GCTCCCTACG | 185705 | EBI3 |
| 30 | 1 | 30 | 11 | 1 | 1 | 0 | AGTGCCGTGT | 76391 | Interferon-inducible protein p75 |
| 27 | 0 | 27 | 0 | 0 | 0 | 0 | CATCTCACTC | No match | |
| 27 | 0 | 27 | 0 | 0 | 0 | 0 | GCCCTGCTAC | 50002 | ELC |
| 26 | 0 | 26 | 54 | 4 | 1 | 1 | GCTTGCAAAA | 177781 | Superoxide dismutase 2 |
| 26 | 1 | 26 | 1 | 0 | 1 | 0 | CCTCCCTGCT | 90790 | ESTs |
| 25 | 1 | 25 | 0 | 0 | 0 | 0 | TGTTTCCTTA | 10887 | DC-LAMP |
| 25 | 1 | 25 | 20 | 4 | 2 | 0 | GGGTTTGTTT | 75889 | Proline-rich protein with nuclear targeting signal |
| 25 | 1 | 25 | 13 | 49 | 6 | 3 | TCACAGCTGT | 77054 | B-cell translocation gene 1, antiproliferative |
| 24 | 0 | 24 | 0 | 0 | 0 | 24 | TAAATCCAAA | 224982 | ESTs |
| 23 | 2 | 46 | 1 | 0 | 0 | 0 | GATCAATCAG | 16530 | PARC |
| 22 | 1 | 22 | 0 | 0 | 0 | 0 | GTGCCTTTTT | 204290 | cDNA DKFZp588N2119 |
| 21 | 0 | 21 | 0 | 0 | 0 | 0 | GCGGCTCCTG | No match | |
| 21 | 0 | 21 | 3 | 1 | 0 | 0 | AACCCCTGGA | 255647 | ESTs |
| 21 | 0 | 21 | 7 | 0 | 0 | 0 | AGCGGCTACA | 183487 | HEM46 (interferon-stimulated gene 20 kd) |
| 21 | 1 | 21 | 0 | 0 | 0 | 0 | GGCAGCCAGA | 75061 | MacMARCKS |
| 21 | 1 | 21 | 0 | 0 | 0 | 5 | AGCAAATCCA | No match | |
| 20 | 0 | 20 | 2 | 0 | 0 | 0 | CTTGCAAACC | 229838 | ESTs |
| 20 | 1 | 20 | 8 | 11 | 2 | 6 | ATCCCTCAGT | 181243 | Activating transcription factor 4 |
| 18 | 18 | 338 | 12 | 0 | 4 | 65 | AACGGGGCCC | 97203 | MDC |
| 17 | 0 | 17 | 11 | 2 | 1 | 0 | GTCTTAAAGT | 177781 | Superoxide dismutase 2, mitochondrial |
| 16 | 0 | 16 | 7 | 4 | 0 | 0 | TCCGCAAGGT | 37617 | ESTs |
| 16 | 1 | 16 | 0 | 0 | 0 | 0 | GCAGGCCAAG | Multiple match | |
| 15 | 7 | 108 | 24 | 14 | 70 | 30 | CGCCGACGAT | 21205 | Interferon-α–inducible protein (clone IFI-6-16) |
| 14 | 0 | 14 | 0 | 0 | 0 | 0 | TCTGTTGGAC | 218318 | ESTs |
| 14 | 0 | 14 | 6 | 0 | 0 | 0 | CAGGTGAAAC | Multiple match | |
| 14 | 1 | 14 | 4 | 6 | 1 | 3 | CCCCTGGCTG | 920 | Modulator recognition factor I |
| 14 | 8 | 110 | 21 | 6 | 11 | 7 | TCCGTGGTTG | 79518 | Neuronal tissue–enriched acidic protein |
| 13 | 0 | 13 | 0 | 8 | 0 | 0 | TTTGGGACCC | 270 | Sec7 and coiled/cell domains, binding protein |
| 12 | 68 | 831 | 15 | 0 | 0 | 1 | GGCACAAAGG | 86742 | TARC |
| 12 | 0 | 12 | 0 | 1 | 0 | 0 | CAGCCTGCGA | 35140 | Serine/threonine kinase 4 |
| 12 | 0 | 12 | 0 | 0 | 0 | 4 | GCAAATCCAA | No match | |
| 12 | 0 | 12 | 2 | 1 | 0 | 0 | ACCATTGGAT | 146360 | Interferon-induced protein 17 |
| 12 | 0 | 12 | 5 | 0 | 1 | 0 | GACAGATGGA | 83575 | ESTs |
| 12 | 1 | 12 | 0 | 0 | 0 | 0 | TTTCATCGTA | 106149 | ESTs |
| 12 | 1 | 12 | 0 | 1 | 0 | 0 | TGTGGAAACC | 80205 | plm-2 oncogene |
| 12 | 1 | 12 | 1 | 0 | 3 | 5 | ATGGTCTACG | 98593 | ESTs |
| 12 | 1 | 12 | 1 | 10 | 0 | 2 | GTGCCCGTGC | 83846 | Trisephosphate isomerase 1 |
| 12 | 5 | 59 | 59 | 1 | 15 | 11 | ACTGTGGCGG | 112242 | ESTs |
The 50 transcripts displaying the largest increase in expression are listed. MADCs are listed by fold induction. n indicates the number of times the tag was identified. Conditions are described in Figure 2. More information is available on the Internet athttp://www.prevent.m.u-tokyo.ac.jp/SAGE.html/. In this table, each number of tags from IMDC (58 540), MADC (31 837), LPS-Mo (31 837, LPS-stimulated monocytes), Mo (57 580, monocytes), M-CSF (55 956, M-CSF–induced macrophages), and GM-CSF (57 483, GM-CSF–induced macrophages) was normalized to 31 837.