Comparison of disease characteristics between the 219 LPHD and 115 LRCHD patients of the present series with those of 773 CHD cases (nodular sclerosis/NS and mixed cellularity/MC) from the multicenter trials of the German Hodgkin Study Group
. | LPHD (n = 219) . | LRCHD (n = 115) . | GHSG CHD/NS (n = 599) . | GHSG CHD/MC (n = 174) . |
---|---|---|---|---|
Age > 50 years | 18% | 32% | 10% | 21% |
Sex: male | 74% | 69% | 49% | 73% |
Stage at diagnosis | ||||
I | 53% | 46% | 10% | 21% |
II | 28% | 24% | 47% | 32% |
III | 14% | 24% | 29% | 35% |
IV | 6% | 6% | 14% | 13% |
Mediastinal involvement | 7% | 15% | 80% | 40% |
Bulky disease | 13% | 11% | 54% | 40% |
B-symptoms | 10% | 11% | 42% | 35% |
. | LPHD (n = 219) . | LRCHD (n = 115) . | GHSG CHD/NS (n = 599) . | GHSG CHD/MC (n = 174) . |
---|---|---|---|---|
Age > 50 years | 18% | 32% | 10% | 21% |
Sex: male | 74% | 69% | 49% | 73% |
Stage at diagnosis | ||||
I | 53% | 46% | 10% | 21% |
II | 28% | 24% | 47% | 32% |
III | 14% | 24% | 29% | 35% |
IV | 6% | 6% | 14% | 13% |
Mediastinal involvement | 7% | 15% | 80% | 40% |
Bulky disease | 13% | 11% | 54% | 40% |
B-symptoms | 10% | 11% | 42% | 35% |
LPHD, lymphocyte predominance Hodgkin disease; LRCHD, lymphocyte-rich classical Hodgkin disease; CHD, classical Hodgkin disease; GHSG, German Hodgkin Study Group.