Table 8.

Comparison of disease characteristics between the 219 LPHD and 115 LRCHD patients of the present series with those of 773 CHD cases (nodular sclerosis/NS and mixed cellularity/MC) from the multicenter trials of the German Hodgkin Study Group

LPHD
(n = 219)
LRCHD (n = 115)GHSG CHD/NS (n = 599)GHSG CHD/MC (n = 174)
Age > 50 years 18% 32% 10% 21%  
Sex: male 74% 69% 49% 73%  
Stage at diagnosis     
 I 53% 46% 10% 21% 
 II 28% 24% 47% 32% 
 III 14% 24% 29% 35% 
 IV 6% 6% 14% 13%  
Mediastinal involvement 7% 15% 80% 40%  
Bulky disease 13% 11% 54% 40% 
B-symptoms 10% 11% 42% 35% 
LPHD
(n = 219)
LRCHD (n = 115)GHSG CHD/NS (n = 599)GHSG CHD/MC (n = 174)
Age > 50 years 18% 32% 10% 21%  
Sex: male 74% 69% 49% 73%  
Stage at diagnosis     
 I 53% 46% 10% 21% 
 II 28% 24% 47% 32% 
 III 14% 24% 29% 35% 
 IV 6% 6% 14% 13%  
Mediastinal involvement 7% 15% 80% 40%  
Bulky disease 13% 11% 54% 40% 
B-symptoms 10% 11% 42% 35% 

LPHD, lymphocyte predominance Hodgkin disease; LRCHD, lymphocyte-rich classical Hodgkin disease; CHD, classical Hodgkin disease; GHSG, German Hodgkin Study Group.

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