Immunophenotype of the neoplastic cells in the 115 LRCHD cases as well as in the observed growth patterns and association with EBV infection
Antigen . | All LRCHD cases (n = 115) positive findings . | Nodular LRCHD cases (n = 80) positive findings . | Interfollicular and diffuse LRCHD cases (n = 35) positive findings . | |||
---|---|---|---|---|---|---|
No. . | % . | No. . | % . | No. . | % . | |
CD20 | 37 | 32 | 26 | 32.5 | 11 | 31 |
CD79a | 15 | 13 | 7 | 8.7 | 2 | 6 |
J-chain | 0 | 0 | 0 | 0 | 0 | 0 |
CD30 | 107 | 98 | 74 | 92.5 | 32 | 91 |
CD15 | 85 | 74 | 65 | 81 | 25 | 71 |
EMA | 7 | 6 | 2 | 2.5 | 4 | 11 |
EBER-transcripts | 46 | 47 | 29 | 41 | 17 | 61 |
Antigen . | All LRCHD cases (n = 115) positive findings . | Nodular LRCHD cases (n = 80) positive findings . | Interfollicular and diffuse LRCHD cases (n = 35) positive findings . | |||
---|---|---|---|---|---|---|
No. . | % . | No. . | % . | No. . | % . | |
CD20 | 37 | 32 | 26 | 32.5 | 11 | 31 |
CD79a | 15 | 13 | 7 | 8.7 | 2 | 6 |
J-chain | 0 | 0 | 0 | 0 | 0 | 0 |
CD30 | 107 | 98 | 74 | 92.5 | 32 | 91 |
CD15 | 85 | 74 | 65 | 81 | 25 | 71 |
EMA | 7 | 6 | 2 | 2.5 | 4 | 11 |
EBER-transcripts | 46 | 47 | 29 | 41 | 17 | 61 |
LRCHD, lymphocyte-rich classical Hodgkin disease; EMA, epithelial membrane antigen; EBER, EBV-encoded RNA.
The percentages have been calculated from assessable cases.