Histologic and immunohistologic characteristics of the 7 cases of LPHD with diffuse growth pattern
Morphology of neoplastic cells | ||
• L&H-cell features | 7 | (100%) |
Immunophenotype of neoplastic cells | ||
• CD20 | 7 | (100%) |
• CD79a | 5 | (71%) |
• J-chain | 4 | (67%) |
• EMA | 6 | (86%) |
Immunohistologic features | ||
• Neoplastic cells arranged in a vaguely nodular fashion | 6 | (86%) |
• Single small foci of small B cells | 3 | (43%) |
• Few scattered CD57+cells with focal condensation | 3 | (43%) |
• CD21+ follicular dendritic cells | 0 | (0%) |
Morphology of neoplastic cells | ||
• L&H-cell features | 7 | (100%) |
Immunophenotype of neoplastic cells | ||
• CD20 | 7 | (100%) |
• CD79a | 5 | (71%) |
• J-chain | 4 | (67%) |
• EMA | 6 | (86%) |
Immunohistologic features | ||
• Neoplastic cells arranged in a vaguely nodular fashion | 6 | (86%) |
• Single small foci of small B cells | 3 | (43%) |
• Few scattered CD57+cells with focal condensation | 3 | (43%) |
• CD21+ follicular dendritic cells | 0 | (0%) |
LPHD, lymphocyte predominance Hodgkin's disease; EMA, epithelial membrane antigen.