Table 1.

Details of 8 novel ATRA–up-regulated genes

Gene name, perm (temp)Length, bpORF, bpPeptides, aaHomologyAccession No.
hUCE(RIG-A1223 48-506 153 mouse UBcM4 AF061736 
hLAP(RIG-B2147 187-1743 519 leucine amino peptidase AF061738 
hWSB-1(RIG-C2048 266-1528 421 mouse WSB-1 AF069313 
hPTP(RIG-D3610 73-2493 807 mouse hematopoietic cell protein tyrosine phosphatase AF077031 
hRD(RIG-H1390 8-976 323 rat retinol dehydrogenase type III AF067174 
SIH001(RIG-J1613 245-802 186 mouse FMLCl1 (28.7% identities in 115 aa) AF061739 
SIH002(RIG-K4347 0-2319 773 human titin (31.2% identities in 415 aa) AF077041 
SIH003(RIG-L2107 381-1331 317 human ubiquitin C-terminal hydrolase
(42.1% identities in 133 aa) 
AF077040 
Gene name, perm (temp)Length, bpORF, bpPeptides, aaHomologyAccession No.
hUCE(RIG-A1223 48-506 153 mouse UBcM4 AF061736 
hLAP(RIG-B2147 187-1743 519 leucine amino peptidase AF061738 
hWSB-1(RIG-C2048 266-1528 421 mouse WSB-1 AF069313 
hPTP(RIG-D3610 73-2493 807 mouse hematopoietic cell protein tyrosine phosphatase AF077031 
hRD(RIG-H1390 8-976 323 rat retinol dehydrogenase type III AF067174 
SIH001(RIG-J1613 245-802 186 mouse FMLCl1 (28.7% identities in 115 aa) AF061739 
SIH002(RIG-K4347 0-2319 773 human titin (31.2% identities in 415 aa) AF077041 
SIH003(RIG-L2107 381-1331 317 human ubiquitin C-terminal hydrolase
(42.1% identities in 133 aa) 
AF077040 

The major structural features of the 8 novel genes in the present work, including their temporary name of RIG (retinoic acid–induced gene), nucleic acid sequences, open reading frames (ORFs), and deduced amino acid sequences, are now available in GenBank.

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