Age-adjusted dosages for intrathecal therapy
| . | <1 y . | 1 y . | 2 y . | 3-8 y . | >9 y . |
|---|---|---|---|---|---|
| HC (mg) | 7.5 | 8 | 10 | 12 | 15 |
| MTX (mg) | 7.5 | 8 | 10 | 12 | 15 |
| ARA-C (mg) | 15 | 16 | 20 | 24 | 30 |
| . | <1 y . | 1 y . | 2 y . | 3-8 y . | >9 y . |
|---|---|---|---|---|---|
| HC (mg) | 7.5 | 8 | 10 | 12 | 15 |
| MTX (mg) | 7.5 | 8 | 10 | 12 | 15 |
| ARA-C (mg) | 15 | 16 | 20 | 24 | 30 |
HC = hydrocortisone; MTX = methotrexate; ARA-C = cytosine arabinoside; CNS = central nervous system.
CNS disease at diagnosis: weekly IT therapy for a total of 5 doses.