Table 1.

Acid hydrolases in human spleen

Control spleens (n = 3)Gaucher's spleens (n = 4)
Acp 5 2.6 ± 0.2 24 ± 13 
Chitotriosidase 1.2 ± 0.7 × 103 3.8 ± 2.0 × 107 
Cathepsin   
 B 26 ± 4.1 183 ± 35 
 K 10 ± 2.0 97 ± 39 
 S 4.0 ± 2.1 91 ± 45  
Immunoreactive cathepsin B 0.16, 0.18* 3.8 ± 0.9 
Control spleens (n = 3)Gaucher's spleens (n = 4)
Acp 5 2.6 ± 0.2 24 ± 13 
Chitotriosidase 1.2 ± 0.7 × 103 3.8 ± 2.0 × 107 
Cathepsin   
 B 26 ± 4.1 183 ± 35 
 K 10 ± 2.0 97 ± 39 
 S 4.0 ± 2.1 91 ± 45  
Immunoreactive cathepsin B 0.16, 0.18* 3.8 ± 0.9 

Measurements are given as nmol/min/mg protein (mean plus or minus SD), except for immunoreactive cathepsin B, which is measured as ng/mg protein. For Gaucher spleen, P < .01.

*

 Indicates n = 2.

 Indicates n = 3.

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