α2β1 expression, platelet adhesion to collagen, simplate bleeding time, and threshold concentrations of collagen for platelets to adhere according to α2 C807 T genotype
| . | α2 genotype . | |
|---|---|---|
| C807 . | C807T + 807T . | |
| n | 17 | 13 + 1 |
| GP-α2β1 density (MIF)* | 17.6 (1.4) | 33.0 (2.6)† |
| Adhesion to collagen | ||
| Type I (% coverage)* | 26.9 (3.1) | 32.2 (2.8) |
| Type III (% coverage)* | 26.1 (1.8) | 28.6 (1.4) |
| Type IV (% coverage)* | 8.9 (2.7) | 20.4 (2.8)‡ |
| Simplate bleeding time (min)* | 7.2 (0.5) | 7.8 (0.6) |
| Threshold value (μg/mL)* | ||
| Collagen type I | 2.79 (0.40) | 2.64 (0.32) |
| Collagen type III | 2.53 (0.24) | 2.25 (0.20) |
| . | α2 genotype . | |
|---|---|---|
| C807 . | C807T + 807T . | |
| n | 17 | 13 + 1 |
| GP-α2β1 density (MIF)* | 17.6 (1.4) | 33.0 (2.6)† |
| Adhesion to collagen | ||
| Type I (% coverage)* | 26.9 (3.1) | 32.2 (2.8) |
| Type III (% coverage)* | 26.1 (1.8) | 28.6 (1.4) |
| Type IV (% coverage)* | 8.9 (2.7) | 20.4 (2.8)‡ |
| Simplate bleeding time (min)* | 7.2 (0.5) | 7.8 (0.6) |
| Threshold value (μg/mL)* | ||
| Collagen type I | 2.79 (0.40) | 2.64 (0.32) |
| Collagen type III | 2.53 (0.24) | 2.25 (0.20) |