Table 3. Phenotypic characterization of... | American Society of Hematology

Table 3.

Phenotypic characterization of CD8⁺ T cells in various lymphoid compartments of SIVmac-infected rhesus monkeys

Cell subset	% CD8⁺ T cells staining^3-150
	575					3KI					IPI					297
	LNs	Sp	BM	Ton	Thy	LNs	Sp	BM	Ton	Thy	LNs	Sp	BM	Ton	Thy	LNs	Sp	BM	Ton	Thy
CD11a+	84	93	81	88	NT^3-151	94	99	94	97	NT	99	98	98	98	95	36	61	NT	25	97
CD28+	51	11	21	23	NT	63	36	29	68	NT	88	75	64	88	85	81	49	66	53	90
CD45RA+	27	14	11	NT	NT	17	16	13	17	NT	26	20	22	25	1.5	55	51	17	84	3.3
CD49d+	90	91	93	NT	NT	90	97	93	90	NT	89	91	98	90	97	95	80	NT	NT	98
CD62L+	24	3.3	2.7	NT	NT	13	4.8	5.3	12	NT	28	19	11	19	65	57	14	32	37	62
CD95+	90	98	98	NT	NT	95	97	98	95	NT	97	99	98	97	87	39	64	NT	28	3.1
MHC class II DR+	60	85	58	NT	NT	78	94	90	83	NT	76	87	78	68	30	25	61	54	23	34

Cell subset	% CD8⁺ T cells staining^3-150
	575					3KI					IPI					297
	LNs	Sp	BM	Ton	Thy	LNs	Sp	BM	Ton	Thy	LNs	Sp	BM	Ton	Thy	LNs	Sp	BM	Ton	Thy
CD11a+	84	93	81	88	NT^3-151	94	99	94	97	NT	99	98	98	98	95	36	61	NT	25	97
CD28+	51	11	21	23	NT	63	36	29	68	NT	88	75	64	88	85	81	49	66	53	90
CD45RA+	27	14	11	NT	NT	17	16	13	17	NT	26	20	22	25	1.5	55	51	17	84	3.3
CD49d+	90	91	93	NT	NT	90	97	93	90	NT	89	91	98	90	97	95	80	NT	NT	98
CD62L+	24	3.3	2.7	NT	NT	13	4.8	5.3	12	NT	28	19	11	19	65	57	14	32	37	62
CD95+	90	98	98	NT	NT	95	97	98	95	NT	97	99	98	97	87	39	64	NT	28	3.1
MHC class II DR+	60	85	58	NT	NT	78	94	90	83	NT	76	87	78	68	30	25	61	54	23	34

F3-150

Values represent the percentages of lymph nodes (LNs) [median of % in lymph nodes that were sampled simultaneously (mandibular, axillary, inguinal, mesenteric, iliac)], spleen (Sp), bone marrow (BM), tonsil (Ton), and thymus (Thy) cells staining for expression of CD11a, CD28, CD45RA, CD49d, CD62L, CD95, and MHC class II-DR on CD8⁺ T cells. CD8⁺ T cells are defined by gating on CD8αβ⁺ CD3⁺ cells.

F3-151

NT, not tested.

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