Table 1.

Binding of the tetrameric Mamu-A*01/p11C, C-M complex to freshly isolated lymph node CD8+ T cells simultaneously sampled from different anatomic compartments of SIVmac-infected,Mamu-A*01+ rhesus monkeys

MonkeysPBLLymph nodes
MandibularAxillaryInguinalMesentericIliac
575 5.3* 15.4 4.3 3.0 2.7 5.6 
3KI 1.3 1.3 2.3 1.1 2.8 4.0 
IPI 6.0 5.6 4.5 6.4 7.7 4.6 
297 6.2 6.3 6.2 8.6 6.2 4.9 
MonkeysPBLLymph nodes
MandibularAxillaryInguinalMesentericIliac
575 5.3* 15.4 4.3 3.0 2.7 5.6 
3KI 1.3 1.3 2.3 1.1 2.8 4.0 
IPI 6.0 5.6 4.5 6.4 7.7 4.6 
297 6.2 6.3 6.2 8.6 6.2 4.9 
*

Percent staining by tetrameric Mamu-A*01/p11C, C-M complex on CD8+ T cells. CD8+ T cells are defined by gating on CD8αβ+ CD3+ cells. p11C, C-M represents the 9-amino acid fragment optimal epitope of the SIV Gag 12-amino acid peptide p11C.

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