Absorption with SakSTAR variants of antibodies elicited with SakSTAR variants in patients with peripheral arterial occlusion (%)
Treatment . | n . | Absorbant . | Insolubilized compound . | |||||
---|---|---|---|---|---|---|---|---|
WT . | SY19 . | SY141 . | SY145 . | SY151 . | SY155 . | |||
WT | Pool 40 | WT | +A | + | + | + | + | + |
SY19 | 59 | + | + | + | + | + | ||
SY141 | 24 | 45 | + | 66 | 70 | 59 | ||
SY145 | 31 | 55 | + | + | 91 | 73 | ||
SY151 | 34 | 54 | 90 | 84 | + | 70 | ||
SY155 | 36 | 69 | + | + | + | + | ||
SY19 | 4 | WT | 94 | 92 | + | + | + | + |
SY19 | 92 | +A | + | + | + | + | ||
SY141 | 41 | 70 | 90 | 85 | 88 | 86 | ||
SY145 | 78 | + | + | + | + | + | ||
SY151 | 80 | + | + | + | + | + | ||
SY155 | 83 | + | + | + | + | + | ||
SY141 | 3 | WT | 87 | + | + | 94 | + | + |
SY19 | 87 | + | + | + | + | + | ||
SY141 | 53B | 72 | 85A | 80 | 77 | 78 | ||
SY145 | 83 | 90 | + | 93 | 93 | 94 | ||
SY151 | 81 | 85 | + | + | + | + | ||
SY155 | 82 | 92 | + | + | + | + | ||
SY145 | 3 | WT | + | + | + | 93 | 92 | 92 |
SY19 | 81 | + | 93 | 90 | 92 | 89 | ||
SY141 | 66 | 73 | 79 | 76 | 77 | 78 | ||
SY145 | 73B | 82 | 94 | 91A | 90 | 90 | ||
SY151 | 71 | 78 | 93 | 88 | 88 | 88 | ||
SY155 | 78 | 83 | 94 | 93 | 93 | 94 | ||
SY151 | 4 | WT | + | + | + | + | + | + |
SY19 | + | + | + | + | + | + | ||
SY141 | 83 | 83 | 93 | 92 | 93 | 89 | ||
SY145 | 87 | 87 | + | + | + | 93 | ||
SY151 | 88 | 91 | + | + | +A | 94 | ||
SY155 | 87 | 90 | + | + | + | + | ||
SY155 | 4 | WT | + | + | + | + | + | + |
SY19 | + | + | + | + | + | + | ||
SY141 | 84 | 87 | + | 89 | 89 | 90 | ||
SY145 | 92 | 94 | + | + | + | + | ||
SY151 | 92 | 94 | + | + | + | + | ||
SY155 | 94 | + | + | + | + | +A |
Treatment . | n . | Absorbant . | Insolubilized compound . | |||||
---|---|---|---|---|---|---|---|---|
WT . | SY19 . | SY141 . | SY145 . | SY151 . | SY155 . | |||
WT | Pool 40 | WT | +A | + | + | + | + | + |
SY19 | 59 | + | + | + | + | + | ||
SY141 | 24 | 45 | + | 66 | 70 | 59 | ||
SY145 | 31 | 55 | + | + | 91 | 73 | ||
SY151 | 34 | 54 | 90 | 84 | + | 70 | ||
SY155 | 36 | 69 | + | + | + | + | ||
SY19 | 4 | WT | 94 | 92 | + | + | + | + |
SY19 | 92 | +A | + | + | + | + | ||
SY141 | 41 | 70 | 90 | 85 | 88 | 86 | ||
SY145 | 78 | + | + | + | + | + | ||
SY151 | 80 | + | + | + | + | + | ||
SY155 | 83 | + | + | + | + | + | ||
SY141 | 3 | WT | 87 | + | + | 94 | + | + |
SY19 | 87 | + | + | + | + | + | ||
SY141 | 53B | 72 | 85A | 80 | 77 | 78 | ||
SY145 | 83 | 90 | + | 93 | 93 | 94 | ||
SY151 | 81 | 85 | + | + | + | + | ||
SY155 | 82 | 92 | + | + | + | + | ||
SY145 | 3 | WT | + | + | + | 93 | 92 | 92 |
SY19 | 81 | + | 93 | 90 | 92 | 89 | ||
SY141 | 66 | 73 | 79 | 76 | 77 | 78 | ||
SY145 | 73B | 82 | 94 | 91A | 90 | 90 | ||
SY151 | 71 | 78 | 93 | 88 | 88 | 88 | ||
SY155 | 78 | 83 | 94 | 93 | 93 | 94 | ||
SY151 | 4 | WT | + | + | + | + | + | + |
SY19 | + | + | + | + | + | + | ||
SY141 | 83 | 83 | 93 | 92 | 93 | 89 | ||
SY145 | 87 | 87 | + | + | + | 93 | ||
SY151 | 88 | 91 | + | + | +A | 94 | ||
SY155 | 87 | 90 | + | + | + | + | ||
SY155 | 4 | WT | + | + | + | + | + | + |
SY19 | + | + | + | + | + | + | ||
SY141 | 84 | 87 | + | 89 | 89 | 90 | ||
SY145 | 92 | 94 | + | + | + | + | ||
SY151 | 92 | 94 | + | + | + | + | ||
SY155 | 94 | + | + | + | + | +A |
Results represent mean values of n patients. Absorption ≥ 95% is represented by +. WT: wild-type SakSTAR. Code identification in Table 3. For an explanation of superscripts A and B, see “Absorption with SakSTAR variants of antibodies elicited in patients by treatment with SakSTAR variants.”