Table 3.

Biodistribution of SS2 and monomer in kidney liver and heart tissue

Organ % Injected dose per gram
SS2 Monomer
Kidney  20.8 ± 2.33-150 34.5 ± 6.4 
Liver  29.2 ± 2.8  25.1 ± 3.3  
Heart 4.1 ± 1.04  3.5 ± 0.5 
Organ % Injected dose per gram
SS2 Monomer
Kidney  20.8 ± 2.33-150 34.5 ± 6.4 
Liver  29.2 ± 2.8  25.1 ± 3.3  
Heart 4.1 ± 1.04  3.5 ± 0.5 
F3-150

P < .002 compared with monomer.

SS2 and monomer were radiolabeled with 125I and 0.074 Mbq (2 μCi) were injected intravenously into C57BL/6 mice (n = 5 per group). After 30 minutes, organs were removed and counted. Data are presented as % injected dose per gram (mean ± 1 SD unit). Groups were compared using the Student t test.

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