Table 1.

Effect of dCF on survival times of mice inoculated with U937 cells

ExperimentDose (mg/kg)No. of miceSurvival (d ± SD)T/C
10 22.0  ±  3.6  
 0.025 10 23.7  ±  3.2 108 
 0.25 10 25.2  ±  7.2 115 
 2.5 10 29.2  ±  7.7* 133  
II 21.5  ±  5.4  
 0.25 28.6  ±  13.1* 134 
 2.5 31.2  ±  16.7* 145 
ExperimentDose (mg/kg)No. of miceSurvival (d ± SD)T/C
10 22.0  ±  3.6  
 0.025 10 23.7  ±  3.2 108 
 0.25 10 25.2  ±  7.2 115 
 2.5 10 29.2  ±  7.7* 133  
II 21.5  ±  5.4  
 0.25 28.6  ±  13.1* 134 
 2.5 31.2  ±  16.7* 145 

Nude mice were inoculated with 3 × 106 U937 cells and treated with dCF 3 times per week. T/C indicates survival of treated mice as a percentage of that in the control.

*

P < .05, using Student t test.

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