Table 1.

Lymphoid cell count numbers in mutant and wild-type mice

AF4+/− AF4−/−
Weight (g)  18.2 ± 1.70 11.83 ± 1.8* 
Spleen (106)  47.8 ± 3.65 32.16 ± 8.9  
Bone marrow (10637.7 ± 10.4  27.70 ± 10.3  
Thymus  
 Thymocytes (106)  234 ± 36.1  100.1 ± 38.2 
 DN (106)  3.25 ± 0.37  3.47 ± 0.34  
 DP (106)  217.17 ± 7.53  86.17 ± 13.85 
 SP CD4+ (106)  23.33 ± 0.71 7.33 ± 1.77 
 SP CD8+ (1064.55 ± 0.12  1.33 ± 0.17 
Bone marrow 
 B220+ (106)  13.75 ± 2.58 8.5 ± 2.5* 
 CD43+ (1060.89 ± 0.01  1.02 ± 0.32  
 CD43(106)  12.33 ± 2.04  8.3 ± 1.44* (n = 5) 
 IgM+ (106)  4.28 ± 0.31 4.14 ± 0.66  
 IgM (1068.62 ± 0.84  4.35 ± 0.82 
AF4+/− AF4−/−
Weight (g)  18.2 ± 1.70 11.83 ± 1.8* 
Spleen (106)  47.8 ± 3.65 32.16 ± 8.9  
Bone marrow (10637.7 ± 10.4  27.70 ± 10.3  
Thymus  
 Thymocytes (106)  234 ± 36.1  100.1 ± 38.2 
 DN (106)  3.25 ± 0.37  3.47 ± 0.34  
 DP (106)  217.17 ± 7.53  86.17 ± 13.85 
 SP CD4+ (106)  23.33 ± 0.71 7.33 ± 1.77 
 SP CD8+ (1064.55 ± 0.12  1.33 ± 0.17 
Bone marrow 
 B220+ (106)  13.75 ± 2.58 8.5 ± 2.5* 
 CD43+ (1060.89 ± 0.01  1.02 ± 0.32  
 CD43(106)  12.33 ± 2.04  8.3 ± 1.44* (n = 5) 
 IgM+ (106)  4.28 ± 0.31 4.14 ± 0.66  
 IgM (1068.62 ± 0.84  4.35 ± 0.82 

Results are expressed as mean ± SD. Two-tailed Student Pvalue.

*

P < .01;

P < .001.

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