Survival of CD4/CD3-ζ–transduced peripheral blood mononuclear cells in 14 recipients of gene-modified CD4+and CD8+ T cells
| Day of study . | CD4+ cells . | CD8+ cells . |
|---|---|---|
| 03-150 | 0 ± 0.2 | 1.0 ± 0.2 |
| 1 | 3.0 ± 0.2 | 2.6 ± 0.2 |
| 143-150 | 3.4 ± 0.2 | 3.6 ± 0.3 |
| 15 | 3.5 ± 0.2 | 3.6 ± 0.3 |
| 283-150 | 3.7 ± 0.2 | 3.6 ± 0.2 |
| 29 | 3.9 ± 0.2 | 3.8 ± 0.2 |
| 42 | 3.9 ± 0.2 | 3.7 ± 0.2 |
| 70 | 3.8 ± 0.2 | 3.6 ± 0.2 |
| 84 | 3.5 ± 0.2 | 3.2 ± 0.3 |
| 168 | 3.3 ± 0.2 | 3.3 ± 0.2 |
| 252 | 3.5 ± 0.3 | 3.4 ± 0.3 |
| 336 | 3.0 ± 0.3 | 2.7 ± 0.3 |
| Day of study . | CD4+ cells . | CD8+ cells . |
|---|---|---|
| 03-150 | 0 ± 0.2 | 1.0 ± 0.2 |
| 1 | 3.0 ± 0.2 | 2.6 ± 0.2 |
| 143-150 | 3.4 ± 0.2 | 3.6 ± 0.3 |
| 15 | 3.5 ± 0.2 | 3.6 ± 0.3 |
| 283-150 | 3.7 ± 0.2 | 3.6 ± 0.2 |
| 29 | 3.9 ± 0.2 | 3.8 ± 0.2 |
| 42 | 3.9 ± 0.2 | 3.7 ± 0.2 |
| 70 | 3.8 ± 0.2 | 3.6 ± 0.2 |
| 84 | 3.5 ± 0.2 | 3.2 ± 0.3 |
| 168 | 3.3 ± 0.2 | 3.3 ± 0.2 |
| 252 | 3.5 ± 0.3 | 3.4 ± 0.3 |
| 336 | 3.0 ± 0.3 | 2.7 ± 0.3 |
Values are model-based least-squares means ± SE log10 DNA copy number per 106 cells analyzed.
Indicates day on which cells were infused.