Baseline characteristics of patients with human immunodeficiency virus (HIV) infection who received modified or unmodified CD8+ T cells
| Characteristic . | Modified cells (n = 21) . | Unmodified cells (n = 9) . | P . |
|---|---|---|---|
| Median CD4 count, (range) | 241 (52-746) | 193 (14-674) | .28* |
| HIV RNA† | |||
| Median log10 copies/mL (range) | 3.64 (1.50-5.23) | 3.31 (1.70-6.01) | .87* |
| No. (%) of patients with <50 copies/mL | 3 (14) | 0 | |
| Antiretroviral therapy, no. of patients | |||
| None | 1 | 1 | |
| NRTIs only | 6 | 2 | |
| NRTIs and PI | 14 | 6 |
| Characteristic . | Modified cells (n = 21) . | Unmodified cells (n = 9) . | P . |
|---|---|---|---|
| Median CD4 count, (range) | 241 (52-746) | 193 (14-674) | .28* |
| HIV RNA† | |||
| Median log10 copies/mL (range) | 3.64 (1.50-5.23) | 3.31 (1.70-6.01) | .87* |
| No. (%) of patients with <50 copies/mL | 3 (14) | 0 | |
| Antiretroviral therapy, no. of patients | |||
| None | 1 | 1 | |
| NRTIs only | 6 | 2 | |
| NRTIs and PI | 14 | 6 |
NRTIs indicates nucleoside reverse transcriptase inhibitors; and PI, protease inhibitor.
By Wilcoxon rank-sum test.
HIV RNA values are based on 20 patients in the modified-cell group and 9 in the unmodified-cell group. One recipient of modified cells who did not have a baseline sample available was excluded from the analysis.